Task: Please estimate if the compound with the SMILES COc1ccc(OCc2nnc3n2N=C(c2ccc(OC)cc2)CS3)cc1 is an allosteric inhibitor of the muscarinic acetylcholine receptor M1.
Result: no
Task: Please {#determine|predict|estimate!} if the {#molecule|compound!} with the {SMILES__description} {SMILES#} is {MUV-859__names__noun}.
Result: {MUV-859#no&yes}
COc1ccc(OCc2nnc3n2N=C(c2ccc(OC)cc2)CS3)cc1
COc1ccc(OCc2nnc3n2N=C(c2ccc(OC)cc2)CS3)cc1
3-[(4-methoxyphenoxy)methyl]-6-(4-methoxyphenyl)-7H-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazine