Task: Please estimate if the compound with the SMILES COC(=O)c1cnn2c(C(F)(F)F)cc(-c3ccc(F)cc3)nc12 is an allosteric inhibitor of the M1 receptor.
Result: no
Task: Please {#determine|predict|estimate!} if the {#molecule|compound!} with the {SMILES__description} {SMILES#} is {MUV-859__names__noun}.
Result: {MUV-859#no&yes}
COC(=O)c1cnn2c(C(F)(F)F)cc(-c3ccc(F)cc3)nc12
COC(=O)c1cnn2c(C(F)(F)F)cc(-c3ccc(F)cc3)nc12
methyl 5-(4-fluorophenyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxylate