Task: Please predict if the molecule with the SMILES COc1ccc(N2CCN(C(CNS(=O)(=O)c3cccs3)c3cccnc3)CC2)cc1 is an allosteric inhibitor of the muscarinic acetylcholine receptor M1.
Result: no
Task: Please {#determine|predict|estimate!} if the {#molecule|compound!} with the {SMILES__description} {SMILES#} is {MUV-859__names__noun}.
Result: {MUV-859#no&yes}
COc1ccc(N2CCN(C(CNS(=O)(=O)c3cccs3)c3cccnc3)CC2)cc1
COc1ccc(N2CCN(C(CNS(=O)(=O)c3cccs3)c3cccnc3)CC2)cc1
N-[2-[4-(4-methoxyphenyl)piperazin-1-yl]-2-pyridin-3-ylethyl]thiophene-2-sulfonamide