Task: Please estimate if the compound with the SMILES COc1ccc2nc(N3CCC(O)CC3)c(C#N)cc2c1 is an allosteric inhibitor of the muscarinic acetylcholine receptor M1.
Result: no
Task: Please {#determine|predict|estimate!} if the {#molecule|compound!} with the {SMILES__description} {SMILES#} is {MUV-859__names__noun}.
Result: {MUV-859#no&yes}
COc1ccc2nc(N3CCC(O)CC3)c(C#N)cc2c1
COc1ccc2nc(N3CCC(O)CC3)c(C#N)cc2c1
2-(4-hydroxypiperidin-1-yl)-6-methoxyquinoline-3-carbonitrile