Task: Please estimate if the molecule with the SMILES COc1ccc(N2CCN(CCNC(=O)c3ccc(NC(=O)C4CCCO4)cc3)CC2)cc1 is an allosteric inhibitor of the M1 receptor.
Result: no
Task: Please {#determine|predict|estimate!} if the {#molecule|compound!} with the {SMILES__description} {SMILES#} is {MUV-859__names__noun}.
Result: {MUV-859#no&yes}
COc1ccc(N2CCN(CCNC(=O)c3ccc(NC(=O)C4CCCO4)cc3)CC2)cc1
COc1ccc(N2CCN(CCNC(=O)c3ccc(NC(=O)C4CCCO4)cc3)CC2)cc1
N-[4-[2-[4-(4-methoxyphenyl)piperazin-1-yl]ethylcarbamoyl]phenyl]oxolane-2-carboxamide