Task: Please estimate if the molecule with the SMILES COc1cc(C(=O)Nc2cccc3ncccc23)cc(OC)c1OC is an allosteric inhibitor of the muscarinic acetylcholine receptor M1.
Result: no
Task: Please {#determine|predict|estimate!} if the {#molecule|compound!} with the {SMILES__description} {SMILES#} is {MUV-859__names__noun}.
Result: {MUV-859#no&yes}
COc1cc(C(=O)Nc2cccc3ncccc23)cc(OC)c1OC
COc1cc(C(=O)Nc2cccc3ncccc23)cc(OC)c1OC
3,4,5-trimethoxy-N-quinolin-5-ylbenzamide