Task: Please predict if the compound with the SMILES COc1ccc(CNC(=O)C2CCN(S(=O)(=O)c3cccc4cccnc34)CC2)cc1 is an allosteric inhibitor of the M1 receptor.
Result: no
Task: Please {#determine|predict|estimate!} if the {#molecule|compound!} with the {SMILES__description} {SMILES#} is {MUV-859__names__noun}.
Result: {MUV-859#no&yes}
COc1ccc(CNC(=O)C2CCN(S(=O)(=O)c3cccc4cccnc34)CC2)cc1
COc1ccc(CNC(=O)C2CCN(S(=O)(=O)c3cccc4cccnc34)CC2)cc1
N-[(4-methoxyphenyl)methyl]-1-quinolin-8-ylsulfonylpiperidine-4-carboxamide