Task: Please estimate if the compound with the SMILES COc1ccc(OC)c2c1CC(C)(C)NC2=O is an allosteric modulator of the D1 receptor.
Result: no
Task: Please {#determine|predict|estimate!} if the {#molecule|compound!} with the {SMILES__description} {SMILES#} is {MUV-858__names__noun}.
Result: {MUV-858#no&yes}
COc1ccc(OC)c2c1CC(C)(C)NC2=O
COc1ccc(OC)c2c1CC(C)(C)NC2=O
5,8-dimethoxy-3,3-dimethyl-2,4-dihydroisoquinolin-1-one