Democratic presidential candidate Hillary Clinton Hillary Diane Rodham ClintonSanders: 'I fully expect' fair treatment by DNC in 2020 after 'not quite even handed' 2016 primary Sanders: 'Damn right' I'll make the large corporations pay 'fair share of taxes' Former Sanders campaign spokesman: Clinton staff are 'biggest a--holes in American politics' MORE leads her Republican counterpart, Donald Trump Donald John TrumpHouse committee believes it has evidence Trump requested putting ally in charge of Cohen probe: report Vietnamese airline takes steps to open flights to US on sidelines of Trump-Kim summit Manafort's attorneys say he should get less than 10 years in prison MORE, by 13 points nationally, according to a poll released early Wednesday.

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Clinton leads Trump, 54 to 41 percent, in the CNN/ORC poll completed ahead of Trump's victory in Indiana on Tuesday night, which secured his title as the presumptive GOP nominee.

While Clinton is better trusted than Trump on many top issues such as terrorism, immigration, healthcare and climate change, he leads Clinton, 50 to 45 percent, among who voters say would do a better job handling the economy.

That's the top issue in the poll, with 9 in 10 voters calling it extremely or very important. Overall, however, Trump continues to be viewed more unfavorably than Clinton.

Fifty-six percent of voters view the New York businessman unfavorably, while 41 percent view him favorably. That's compared to 49 percent who view Clinton favorably and an equal percentage who view her unfavorably.

The survey of 1,001 adults and 890 registered voters was conducted April 28 through May 1 with a margin of error of 3.5 points.