Does anyone know which treatments he's planning to test in this funded study -- phenylephedrine, IV saline, ORS, or all three?



A quick glance at the abstract of his phenylephedrin paper makes me wonder if the entire effect is simply raising BP. Anyone know more?





It's good to see he's looking at patients with POTS and those with NMH. It seems the treatment would be different with those different conditions. It will be interesting to see if he can get good results in both. I like that he's actually measuring blood volume rather than just going by symptoms, since neither POTS nor NMH guarantees low blood volume. I want to see an increase in blood volume in patients with distinct low blood volume, not just a small increase of blood volume in patients with normal or near normal blood volume.



Do we know yet what ME/CFS definition he's using to identify patients? After all, POTS and NMH patients my have the symptom chronic fatigue without having ME/CFS. I hope he's actually got well-characterized ME/CFS patients who also have POTS or NMH.



Should be interesting! I hope we see more studies on potential treatments. The big picture is important, but we need some treatment while they're working on the causal and contributing factors.

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