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The free text search will scan for complete and partial matches to gene names, gene synonyms, gene descriptions, external (Ensembl,



Specific fields can be searched by using the "Fields"-function. Available fields are: Gene name (IF=immunoflourescence, WB=Western blot, The search function can be used for free text search (type anything in the search field), or for more complex queries using "Fields" (see examples ).The free text search will scan for complete and partial matches to gene names, gene synonyms, gene descriptions, external ( UniProt NCBI Entrez Gene) gene and protein identifiers, protein classes Gene Ontology identifiers and descriptions, antibody identifiers and image annotations. The free text query word needs to be at least three characters long.Specific fields can be searched by using the "Fields"-function. Available fields are: Gene name ( HGNC name or synonyms), Protein class , Chromosome, External identifier ( Ensembl gene, transcript or protein identifier, UniProt accession number, NCBI Entrez gene identifier), Subcellular location based on immunofluorescent staining in three different cell lines, Organ-, Tissue-, Cancer- and Cell line expression, Antibody validation results in four different assays ( IH=immunohistochemistry PA=Protein array ), evidence scores and a filtration on Genes with antibodies only and Genes with knowledge-based annotated protein expression ( IH IF ). Search Fields »



AND NOT



Field All – GENE INFO – Gene name Protein class Chromosome External id – DATA AVAILABILITY – Has protein data – DATA RELIABILITY – Reliability score tissue (IHC) Reliability score mouse brain Reliability score cells (ICC) – ANTIBODY VALIDATION – Protein array (PA) Western blot (WB) Immunohistochemistry (IHC) Immunocytochemistry (ICC) – PRIMARY DATA – Subcellular localization (ICC) Tissue expression (IHC) Tissue category (RNA) Cell category (RNA) Cancer category (RNA) Tissue detectable (RNA) Cell line detectable (RNA) Cancer detectable (RNA) Prognostic cancer – PROTEIN EVIDENCE – Evidence summary UniProt evidence HPA evidence MS evidence – ANTIBODIES – With antibodies – EXTRA – Sort by Term





Gene name



Class Blood group antigen proteins Cancer-related genes CD markers Citric acid cycle related proteins Disease related genes Enzymes FDA approved drug targets G-protein coupled receptors Mapped to UniProt SWISS-PROT Nuclear receptors Plasma proteins Potential drug targets Predicted intracellular proteins Predicted membrane proteins Predicted secreted proteins Protein evidence (Ezkurdia et al 2014) Protein evidence (Kim et al 2014) RAS pathway related proteins Ribosomal proteins RNA polymerase related proteins Transcription factors Transporters Voltage-gated ion channels



Subclass



Chromosome 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 MT Unmapped X Y



External id



In atlas Tissue Pathology Cell



Reliability Enhanced Supported Approved Uncertain



Reliability Supported Approved



Reliability Enhanced Supported Approved Uncertain



Validation Supported Approved Uncertain



Validation Enhanced - Capture Enhanced - Genetic Enhanced - Independent Enhanced - Orthogonal Enhanced - Recombinant Supported Approved Uncertain



Validation Enhanced - Independent Enhanced - Orthogonal Supported Approved Uncertain



Validation Enhanced - Genetic Enhanced - Independent Enhanced - Recombinant Supported Approved Uncertain



Location Actin filaments Aggresome Cell Junctions Centrosome Cleavage furrow Cytokinetic bridge Cytoplasmic bodies Cytosol Endoplasmic reticulum Endosomes Focal adhesion sites Golgi apparatus Intermediate filaments Lipid droplets Lysosomes Microtubule ends Microtubule organizing center Microtubules Midbody Midbody ring Mitochondria Mitotic spindle Nuclear bodies Nuclear membrane Nuclear speckles Nucleoli Nucleoli fibrillar center Nucleoplasm Nucleus Peroxisomes Plasma membrane Rods & Rings Vesicles



Searches – RELIABILITY – Enhanced Supported Approved Uncertain – SUBCELLULAR VARIATION – Intensity variation Spatial variation Cell cycle intensity correlation Cell cycle spatial correlation Cell cycle biologically Custom data cell cycle dependant – MULTILOCALIZATION – Multilocalizing Localizing 1 Localizing 2 Localizing 3 Localizing 4 Localizing 5 Localizing 6 – OTHER – Main location Additional location



Tissue Any Adrenal gland Appendix Bone marrow Breast Bronchus Cerebellum Cerebral cortex Cervix, uterine Choroid plexus Colon Duodenum Endometrium 1 Endometrium 2 Epididymis Esophagus Eye Fallopian tube Gallbladder Hair Heart muscle Hippocampus Hypothalamus Kidney Lactating breast Liver Lung Lymph node Nasopharynx Oral mucosa Ovary Pancreas Parathyroid gland Pituitary gland Placenta Prostate Rectum Retina Salivary gland Seminal vesicle Skeletal muscle Skin Skin 1 Skin 2 Small intestine Smooth muscle Soft tissue 1 Soft tissue 2 Spleen Stomach 1 Stomach 2 Testis Thymus Thyroid gland Tonsil Urinary bladder Vagina



Cell type



Expression Not detected Low Medium High



Tissue Any Adipose tissue Adrenal gland Appendix Bone marrow Breast Cerebral cortex Cervix, uterine Colon Duodenum Endometrium Epididymis Esophagus Fallopian tube Gallbladder Heart muscle Kidney Liver Lung Lymph node Ovary Pancreas Parathyroid gland Placenta Prostate Rectum Salivary gland Seminal vesicle Skeletal muscle Skin Small intestine Smooth muscle Spleen Stomach Testis Thyroid gland Tonsil Urinary bladder



Specificity Tissue enriched Group enriched Tissue enhanced Elevated Expressed in all Mixed Not detected



Cell line Any A-431 A549 AF22 AN3-CA ASC diff ASC TERT1 BEWO BJ BJ hTERT+ BJ hTERT+ SV40 Large T+ BJ hTERT+ SV40 Large T+ RasG12V CACO-2 CAPAN-2 Daudi EFO-21 FHDF/TERT166 HaCaT HAP1 HBEC3-KT HBF TERT88 HDLM-2 HEK 293 HEL HeLa Hep G2 HHSteC HL-60 HMC-1 HSkMC HTCEpi HTEC/SVTERT24-B HTERT-HME1 HUVEC TERT2 K-562 Karpas-707 LHCN-M2 MCF7 MOLT-4 NB-4 NTERA-2 PC-3 REH RH-30 RPMI-8226 RPTEC TERT1 RT4 SCLC-21H SH-SY5Y SiHa SK-BR-3 SK-MEL-30 T-47d THP-1 TIME U-138 MG U-2 OS U-2197 U-251 MG U-266/70 U-266/84 U-698 U-87 MG U-937 WM-115



Specificity Cell line enriched Group enriched Cell line enhanced Elevated Expressed in all Mixed Not detected



Cancer Any Breast cancer Cervical cancer Colorectal cancer Endometrial cancer Glioma Head and neck cancer Liver cancer Lung cancer Melanoma Ovarian cancer Pancreatic cancer Prostate cancer Renal cancer Stomach cancer Testis cancer Thyroid cancer Urothelial cancer



Specificity Tissue enriched Group enriched Tissue enhanced Elevated Expressed in all Mixed Not detected



Tissue Any Adipose tissue Adrenal gland Appendix Bone marrow Breast Cerebral cortex Cervix, uterine Colon Duodenum Endometrium Epididymis Esophagus Fallopian tube Gallbladder Heart muscle Kidney Liver Lung Lymph node Ovary Pancreas Parathyroid gland Placenta Prostate Rectum Salivary gland Seminal vesicle Skeletal muscle Skin Small intestine Smooth muscle Spleen Stomach Testis Thyroid gland Tonsil Urinary bladder



Detectable Yes No



Cell line Any A-431 A549 AF22 AN3-CA ASC diff ASC TERT1 BEWO BJ BJ hTERT+ BJ hTERT+ SV40 Large T+ BJ hTERT+ SV40 Large T+ RasG12V CACO-2 CAPAN-2 Daudi EFO-21 FHDF/TERT166 HaCaT HAP1 HBEC3-KT HBF TERT88 HDLM-2 HEK 293 HEL HeLa Hep G2 HHSteC HL-60 HMC-1 HSkMC HTCEpi HTEC/SVTERT24-B HTERT-HME1 HUVEC TERT2 K-562 Karpas-707 LHCN-M2 MCF7 MOLT-4 NB-4 NTERA-2 PC-3 REH RH-30 RPMI-8226 RPTEC TERT1 RT4 SCLC-21H SH-SY5Y SiHa SK-BR-3 SK-MEL-30 T-47d THP-1 TIME U-138 MG U-2 OS U-2197 U-251 MG U-266/70 U-266/84 U-698 U-87 MG U-937 WM-115



Detectable Yes No



Cancer Any Breast cancer Cervical cancer Colorectal cancer Endometrial cancer Glioma Head and neck cancer Liver cancer Lung cancer Melanoma Ovarian cancer Pancreatic cancer Prostate cancer Renal cancer Stomach cancer Testis cancer Thyroid cancer Urothelial cancer



Detectable Yes No



Cancer Breast cancer Cervical cancer Colorectal cancer Endometrial cancer Glioma Head and neck cancer Liver cancer Lung cancer Melanoma Ovarian cancer Pancreatic cancer Prostate cancer Renal cancer Stomach cancer Testis cancer Thyroid cancer Urothelial cancer



Prognosis Favourable Unfavourable



Category Evidence at protein level Evidence at transcript level No evidence



Score Evidence at protein level Evidence at transcript level No evidence



Score Evidence at protein level Evidence at transcript level No evidence



Score Evidence at protein level Evidence at transcript level No evidence



Antibodies Yes No



Column gene position tissue specific score prognostic

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