Hillary Clinton Hillary Diane Rodham ClintonSanders: 'I fully expect' fair treatment by DNC in 2020 after 'not quite even handed' 2016 primary Sanders: 'Damn right' I'll make the large corporations pay 'fair share of taxes' Former Sanders campaign spokesman: Clinton staff are 'biggest a--holes in American politics' MORE has opened up a double-digit lead on Donald Trump Donald John TrumpHouse committee believes it has evidence Trump requested putting ally in charge of Cohen probe: report Vietnamese airline takes steps to open flights to US on sidelines of Trump-Kim summit Manafort's attorneys say he should get less than 10 years in prison MORE in a new poll conducted entirely after the release of video in which the Republican nominee talks about groping women without their consent.

The Democratic nominee also eclipsed the 50-percent margin in a head-to-head matchup.

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Clinton leads the GOP nominee 52 percent to 38 percent in the new NBC News/Wall Street Journal poll conducted on Saturday and Sunday. In a four-way matchup, Clinton leads by 11 points, 46 percent to 35 percent, with Libertarian nominee Gary Johnson Gary Earl JohnsonPotential GOP primary challenger: Trump's 'contempt for the American people' behind possible bid The Hill's 12:30 Report — Presented by Kidney Care Partners — Trump escalates border fight with emergency declaration Former Mass. governor takes step toward Trump primary challenge MORE posting 9 percent.

During the last NBC/WSJ poll in September, Clinton led Trump by 7 points in the two-way race and 6 points in the four-way scenario.

Clinton's 14-point margin in the head-to-head and 11-point margin in the four way represent Clinton's largest lead since an August McClatchy/Marist poll. That poll was taken after Clinton's post-convention bounce and as Trump faced criticism over his comments about a Gold Star family.

The results come as Trump continues to face serious criticism from within his own party over the video, which was released Friday. More than two-dozen GOP lawmakers, including Senate Republican Conference Chairman John Thune John Randolph ThunePolls: Hiking estate tax less popular than taxing mega wealth, income Will Trump sign the border deal? Here's what we know Key GOP senator pitches Trump: Funding deal a 'down payment' on wall MORE (S.D.), want him to step aside.

The polls had already been trending in Clinton's direction after a strong performance at the first presidential debate late last month.

While Republicans had hoped Trump could build on running mate Mike Pence Michael (Mike) Richard PencePence meeting with Senate GOP ahead of vote to block emergency declaration 'And the award for best political commentary by an Oscar nominee goes to...' UN nuclear watchdog: Iran maintains compliance with 2015 pact MORE's showing at his own debate last week, the fallout from the video has given Democrats new ammunition and threatens to further derail Trump's campaign.

Since it's only the first major poll released in the aftermath of those comments, it's unclear whether the NBC/WSJ results are indicative of a larger trend or not. But the large lead will likely prompt even more celebration from Democrats, and concern from Republicans.

The new poll also shows worrying results for the GOP’s efforts down-ballot, as 49 percent said they wanted Democrats to control Congress compared to 42 percent who wanted Republican control. Mark Murray, a the senior political editor at NBC News, tweeted that that margin is the highest since the 2013 government shutdown.

NBC and the WSJ surveyed 500 registered voters and the poll has a margin of error of between 4.4 and 4.6 percent depending on the sample.