Won Yong Jung, Haneul Kim, Se Jin Jeon, Hye Jin Park, Hyuck Jai Choi, Nam Jae Kim, Dong Hyun Kim, Dae Sik Jang and Jong Hoon Ryu , Eclalbasaponin II Ameliorates the Cognitive Impairment Induced by Cholinergic Blockade in Mice , Neurochemical Research , 43 , 2 , (351) , .

Nikolaos Pitsikas and Petros A. Tarantilis , Effects of the active constituents of Crocus sativus L. crocins and their combination with memantine on recognition memory in rats , Behavioural Pharmacology , 10.1097/FBP.0000000000000380 , 29 , 5 , (400-412) , .

Ainhoa Oñatibia‐Astibia, Rafael Franco and Eva Martínez‐Pinilla , Health benefits of methylxanthines in neurodegenerative diseases , Molecular Nutrition & Food Research , 61 , 6 , .

Christopher Wilke, David Grosshans, Joseph Duman, Paul Brown and Jing Li , Radiation-induced cognitive toxicity: pathophysiology and interventions to reduce toxicity in adults , Neuro-Oncology , .

Won Yong Jung, Haneul Kim, Ho Jae Park, Se Jin Jeon, Hye Jin Park, Hyuck Jai Choi, Nam Jae Kim, Dae Sik Jang, Dong Hyun Kim and Jong Hoon Ryu , The ethanolic extract of the Eclipta prostrata L. ameliorates the cognitive impairment in mice induced by scopolamine , Journal of Ethnopharmacology , 190 , (165) , .

Kenichi Kakefuda, Mitsue Ishisaka, Kazuhiro Tsuruma, Masamitsu Shimazawa and Hideaki Hara , Memantine, an NMDA receptor antagonist, improves working memory deficits in DGKβ knockout mice , Neuroscience Letters , 630 , (228) , .

Ashok Kumar , NMDA Receptor Function During Senescence: Implication on Cognitive Performance , Frontiers in Neuroscience , 9 , .

Jingyi Ma, Asfandyar Mufti and L. Stan Leung , Effects of memantine on hippocampal long-term potentiation, gamma activity, and sensorimotor gating in freely moving rats , Neurobiology of Aging , 36 , 9 , (2544) , .

Haijie Yang, Sung-Oh Huh and Jae Seung Hong , Enhancement of Short-Term Memory by Methyl-6-(Phenylethynyl)-Pyridine in the BTBR T+tf/J Mouse Model of Autism Spectrum Disorder , Endocrinology and Metabolism , 30 , 1 , (98) , .

S. Beggiato, A. Giuliani, S. Sivilia, L. Lorenzini, T. Antonelli, B.P. Imbimbo, L. Giardino, L. Calzà and L. Ferraro , CHF5074 and LY450139 sub-acute treatments differently affect cortical extracellular glutamate levels in pre-plaque Tg2576 mice , Neuroscience , 266 , (13) , .

Donghyuck Bae, Jihye Kim, Ju-Ryun Na, Yujin Kim, Joon-Yeol Lee and Sunoh Kim , Anti-amnesic Effect of Eriobotrya japonica Leaf Extract on Scopolamine-induced Memory Impairment in Rats , Journal of the Korean Society of Food Science and Nutrition , 43 , 6 , (799) , .

Ike dela Peña, Seo Young Yoon, Hee Jin Kim, Sejin Park, Eun Young Hong, Jong Hoon Ryu, Il Ho Park and Jae Hoon Cheong , Effects of ginseol k-g3, an Rg3-enriched fraction, on scopolamine-induced memory impairment and learning deficit in mice , Journal of Ginseng Research , 38 , 1 , (1) , .

Shakuntala Savanthrapadian, Amy R. Wolff, Barbara J. Logan, Michael J. Eckert, David K. Bilkey and Wickliffe C. Abraham , Enhanced hippocampal neuronal excitability and LTP persistence associated with reduced behavioral flexibility in the maternal immune activation model of schizophrenia , Hippocampus , 23 , 12 , (1395-1409) , .

Akira Nagakura, Yoshitsugu Shitaka, Junko Yarimizu and Nobuya Matsuoka , Characterization of cognitive deficits in a transgenic mouse model of Alzheimer's disease and effects of donepezil and memantine , European Journal of Pharmacology , 703 , 1-3 , (53) , .

Hyung Eun Lee, So Young Lee, Ju Sun Kim, Se Jin Park, Jong Min Kim, Young Woo Lee, Jun Man Jung, Dong Hyun Kim, Bum Young Shin, Dae Sik Jang, Sam Sik Kang and Jong Hoon Ryu , Ethanolic Extract of the Seed of Zizyphus jujuba var. spinosa Ameliorates Cognitive Impairment Induced by Cholinergic Blockade in Mice , Biomolecules and Therapeutics , 21 , 4 , (299) , .

Kanaka Latha Alikatte, Butchi Raju Akondi, Venu Gopal Yerragunta, Prabhakar Reddy Veerareddy and Suresh Palle , Antiamnesic activity of Syzygium cumini against scopolamine induced spatial memory impairments in rats , Brain and Development , 34 , 10 , (844) , .

Gupta Rachna, K. Gupta Lalit, K. Mediratta Pramod and K. Bhattacharya Swapan , Effect of resveratrol on scopolamine-induced cognitive impairment in mice , Pharmacological Reports , 64 , 2 , (438) , .

M Vandesquille, I Carrié, C Louis, D Beracochea and P Lestage , Effects of positive modulators of α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA)-type glutamate receptors in a benzodiazepine-induced deficit of spatial discrimination in mice , Journal of Psychopharmacology , 26 , 6 , (845) , .

Andrea de Bartolomeis, Chiara Sarappa, Salvatore Magara and Felice Iasevoli , Targeting glutamate system for novel antipsychotic approaches: Relevance for residual psychotic symptoms and treatment resistant schizophrenia , European Journal of Pharmacology , 682 , 1-3 , (1) , .

Xiaotong Liu, Dong Hyun Kim, Jong Min Kim, Se Jin Park, Mudan Cai, Dae Sik Jang and Jong Hoon Ryu , The Memory-Ameliorating Effects of Artemisia princeps var. orientalis Against Cholinergic Dysfunction in Mice , The American Journal of Chinese Medicine , 40 , 05 , (993) , .

Jodi R. Samartgis, Leslie Schachte, Agnes Hazi and Simon F. Crowe , Memantine facilitates memory consolidation and reconsolidation in the day-old chick , Neurobiology of Learning and Memory , 97 , 4 , (380) , .

Rachna Gupta and Lalit Kumar Gupta , Improvement in long term and visuo-spatial memory following chronic pioglitazone in mouse model of Alzheimer's disease , Pharmacology Biochemistry and Behavior , 102 , 2 , (184) , .

Ren-wen Han, Rui-san Zhang, Min Chang, Ya-li Peng, Pei Wang, Sheng-quan Hu, Chung-lit Choi, Ming Yin, Rui Wang and Yi-fan Han , Reversal of scopolamine-induced spatial and recognition memory deficits in mice by novel multifunctional dimers bis-cognitins , Brain Research , 1470 , (59) , .

Édina Madeira Flores, Shandale Emanuele Cappelari, Patrícia Pereira and Jaqueline Nascimento Picada , Effects of Memantine, a Non‐Competitive N‐Methyl‐d‐Aspartate Receptor Antagonist, on Genomic Stability , Basic & Clinical Pharmacology & Toxicology , 109 , 5 , (413-417) , .

Matthias Vandesquille, Ali Krazem, Caroline Louis, Pierre Lestage and Daniel Béracochéa , S 18986 reverses spatial working memory impairments in aged mice: comparison with memantine , Psychopharmacology , 215 , 4 , (709) , .

Csaba Nyakas, Ivica Granic, László G. Halmy, Pradeep Banerjee and Paul G.M. Luiten , The basal forebrain cholinergic system in aging and dementia. Rescuing cholinergic neurons from neurotoxic amyloid-β42 with memantine , Behavioural Brain Research , 221 , 2 , (594) , .

Jouni Ihalainen, Timo Sarajärvi, Doug Rasmusson, Susanna Kemppainen, Pekka Keski-Rahkonen, Marko Lehtonen, Pradeep K. Banerjee, Kazue Semba and Heikki Tanila , Effects of memantine and donepezil on cortical and hippocampal acetylcholine levels and object recognition memory in rats , Neuropharmacology , 61 , 5-6 , (891) , .

Jason Lockrow, Heather Boger, Heather Bimonte-Nelson and Ann-Charlotte Granholm , Effects of long-term memantine on memory and neuropathology in Ts65Dn mice, a model for Down syndrome , Behavioural Brain Research , 221 , 2 , (610) , .

Vijayasree V. Giridharan, Rajarajan A. Thandavarayan and Tetsuya Konishi , Effect ofShengmai-sanon Cognitive Performance and Cerebral Oxidative Damage in BALB/c Mice , Journal of Medicinal Food , 14 , 6 , (601) , .

Vijayasree Vayalanellore Giridharan, Rajarajan Amirthalingam Thandavarayan and Tetsuya Konishi , Amelioration of scopolamine induced cognitive dysfunction and oxidative stress by Inonotus obliquus– a medicinal mushroom , Food & Function , 2 , 6 , (320) , .

Xu Jie, Wang Yang, Yu Jie, Jamal Hisham Hashim, Xiao‐Yun Liu, Qi‐Yuan Fan and Li Yan , Toxic effect of gestational exposure to nonylphenol on F1 male rats , Birth Defects Research Part B: Developmental and Reproductive Toxicology , 89 , 5 , (418-428) , .

Won Yong Jung, Se Jin Park, Dong Hyun Park, Jong Min Kim, Dong Hyun Kim and Jong Hoon Ryu , Quercetin impairs learning and memory in normal mice via suppression of hippocampal phosphorylated cyclic AMP response element-binding protein expression , Toxicology Letters , 197 , 2 , (97) , .

Se Jin Park, Dong Hyun Kim, Il Kyun Lee, Won Yong Jung, Dong Hyun Park, Jong Min Kim, Kang Ro Lee, Kyung-Tae Lee, Chan Young Shin, Jae Hoon Cheong, Kwang Ho Ko and Jong Hoon Ryu , The ameliorating effect of the extract of the flower of Prunella vulgaris var. lilacina on drug-induced memory impairments in mice , Food and Chemical Toxicology , 48 , 6 , (1671) , .

Ana Cristina G. Souza, César Augusto Brüning, Marlon Régis Leite, Gilson Zeni and Cristina Wayne Nogueira , Diphenyl diselenide improves scopolamine-induced memory impairment in mice , Behavioural Pharmacology , 21 , 5-6 , (556) , .

Sunita Sharma, Sharlene Rakoczy and Holly Brown-Borg , Assessment of spatial memory in mice , Life Sciences , 87 , 17-18 , (521) , .

Sun-Ho Kim, Dong-Hyun Kim, Ji-Joung Choi, Jong-Gu Lee, Choong-Ho Lee, Se-Jin Park, Won-Yong Jung, Dong-Hyun Park, Kwang-Ho Ko, Seung-Ho Lee and Jong-Hoon Ryu , Forsythiaside, a Constituent of the Fruits of Forsythia suspense, Ameliorates Scopolamine-Induced Memory Impairment in Mice , Biomolecules and Therapeutics , 17 , 3 , (249) , .

Dong Hyun Kim, Sook Kyung Hyun, Byung Hoon Yoon, Ji-Hyung Seo, Kyung-Tae Lee, Jae Hoon Cheong, Seo Yun Jung, Changbae Jin, Jae Sue Choi and Jong Hoon Ryu , Gluco-obtusifolin and Its Aglycon, Obtusifolin, Attenuate Scopolamine-Induced Memory Impairment , Journal of Pharmacological Sciences , 111 , 2 , (110) , .

Yong Kyung Lee, Dong Yeon Yuk, Tae Il Kim, Young Heui Kim, Kyoung Tae Kim, Ki Ho Kim, Beom Jun Lee, Sang-Yoon Nam and Jin Tae Hong , Protective effect of the ethanol extract of Magnolia officinalis and 4-O-methylhonokiol on scopolamine-induced memory impairment and the inhibition of acetylcholinesterase activity , Journal of Natural Medicines , 10.1007/s11418-009-0330-z , 63 , 3 , (274-282) , .

Henrieta Scholtzova, Youssef Z. Wadghiri, Moustafa Douadi, Einar M. Sigurdsson, Yong‐Sheng Li, David Quartermain, Pradeep Banerjee and Thomas Wisniewski , Memantine leads to behavioral improvement and amyloid reduction in Alzheimer's‐disease‐model transgenic mice shown as by micromagnetic resonance imaging , Journal of Neuroscience Research , 86 , 12 , (2784-2791) , .

Hongxin Dong, Carla M Yuede, Carolyn Coughlan, Brian Lewis and John G Csernansky , Effects of Memantine on Neuronal Structure and Conditioned Fear in the Tg2576 Mouse Model of Alzheimer's Disease , Neuropsychopharmacology , 33 , 13 , (3226) , .

Amber M. Muehlmann and Darragh P. Devine , Glutamate-mediated neuroplasticity in an animal model of self-injurious behaviour , Behavioural Brain Research , 10.1016/j.bbr.2007.12.001 , 189 , 1 , (32-40) , .

Tran Manh Hung, Tran Minh Ngoc, Ui Joung Youn, Byung Sun Min, MinKyun Na, Phuong Thien Thuong and KiHwan Bae , Anti-amnestic Activity of Pseudocoptisine from Corydalis Tuber , Biological & Pharmaceutical Bulletin , 31 , 1 , (159) , .

Jorge Camarasa, José M. Marimón, Teresa Rodrigo, Elena Escubedo and David Pubill , Memantine prevents the cognitive impairment induced by 3,4-methylenedioxymethamphetamine in rats , European Journal of Pharmacology , 589 , 1-3 , (132) , .

Arjan Blokland and Frank Boess , Use of behavioural and long-term potentiation models in the development of memory-improving drugs , Expert Opinion on Drug Discovery , 3 , 9 , (1067) , .

Daniel Beracochea, Aurelie Boucard, Caryn Trocme-Thibierge and Philippe Morain , Improvement of contextual memory by S 24795 in aged mice: comparison with memantine , Psychopharmacology , 10.1007/s00213-007-0987-5 , 196 , 4 , (555-564) , .

Chris G. Parsons, Albrecht Stöffler and Wojciech Danysz , Memantine: a NMDA receptor antagonist that improves memory by restoration of homeostasis in the glutamatergic system - too little activation is bad, too much is even worse , Neuropharmacology , 53 , 6 , (699) , .

Nikolaos Pitsikas and Nikolaos Sakellaridis , Memantine and recognition memory: Possible facilitation of its behavioral effects by the nitric oxide (NO) donor molsidomine , European Journal of Pharmacology , 571 , 2-3 , (174) , .

Dong Hyun Kim, Do Yoon Kim, Young Choong Kim, Ji Wook Jung, Seungjoo Lee, Byung Hoon Yoon, Jae Hoon Cheong, Yeong Shik Kim, Sam Sik Kang, Kwang Ho Ko and Jong Hoon Ryu , Nodakenin, a coumarin compound, ameliorates scopolamine-induced memory disruption in mice , Life Sciences , 80 , 21 , (1944) , .

Dong Hyun Kim, Su Jin Jeon, Kun Ho Son, Ji Wook Jung, Seungjoo Lee, Byung Hoon Yoon, Jong-Ju Lee, Young-Wuk Cho, Jae Hoon Cheong, Kwang Ho Ko and Jong Hoon Ryu , The ameliorating effect of oroxylin A on scopolamine-induced memory impairment in mice , Neurobiology of Learning and Memory , 87 , 4 , (536) , .

Carla M. Yuede, Hongxin Dong and John G. Csernansky , Anti-dementia drugs and hippocampal-dependent memory in rodents , Behavioural Pharmacology , 10.1097/FBP.0b013e3282da278d , 18 , 5-6 , (347-363) , .

Dong Hyun Kim, Byung Hoon Yoon, Yong-Won Kim, Seungjoo Lee, Bum Young Shin, Ji Wook Jung, Hyoung Ja Kim, Yong Sup Lee, Jae Sue Choi, Sun Yeou Kim, Kyung-Tae Lee and Jong Hoon Ryu , The Seed Extract of Cassia obtusifolia Ameliorates Learning and Memory Impairments Induced by Scopolamine or Transient Cerebral Hypoperfusion in Mice , Journal of Pharmacological Sciences , 10.1254/jphs.FP0061565 , 105 , 1 , (82-93) , .

Rivka Inzelberg, Ubaldo Bonuccelli, Edna Schechtman, Ala Miniowich, Rosa Strugatsky, Roberto Ceravolo, Chiara Logi, Carlo Rossi, Colin Klein and J. Martin Rabey , Association between amantadine and the onset of dementia in Parkinson's disease , Movement Disorders , 21 , 9 , (1375-1379) , .

Dong Hyun Kim, Tran Manh Hung, Ki Hwan Bae, Ji Wook Jung, Seungjoo Lee, Byung Hoon Yoon, Jae Hoon Cheong, Kwang Ho Ko and Jong Hoon Ryu , Gomisin A improves scopolamine-induced memory impairment in mice , European Journal of Pharmacology , 542 , 1-3 , (129) , .

S. Rosi, A. Vazdarjanova, V. Ramirez-Amaya, P.F. Worley, C. A. Barnes and G.L. Wenk , Memantine protects against LPS-induced neuroinflammation, restores behaviorally-induced gene expression and spatial learning in the rat , Neuroscience , 142 , 4 , (1303) , .

Debby Van Dam and Peter Paul De Deyn , Cognitive evaluation of disease-modifying efficacy of Galantamine and Memantine in the APP23 model , European Neuropsychopharmacology , 16 , 1 , (59) , .

Gary L. Wenk, Chris G. Parsons and Wojciech Danysz , Potential role of N-methyl-D-aspartate receptors as executors of neurodegeneration resulting from diverse insults: focus on memantine , Behavioural Pharmacology , 10.1097/00008877-200609000-00007 , 17 , 5-6 , (411-424) , .

P. Riederer and S. Hoyer , From benefit to damage. Glutamate and advanced glycation end products in Alzheimer brain , Journal of Neural Transmission , 10.1007/s00702-006-0591-6 , 113 , 11 , (1671-1677) , .

José L. Molinuevo, Albert Lladó and Lorena Rami , Memantine: Targeting glutamate excitotoxicity in Alzheimer's disease and other dementias , American Journal of Alzheimer's Disease & Other Dementiasr , 20 , 2 , (77) , .

S.K. Sonkusare, C.L. Kaul and P. Ramarao , Dementia of Alzheimer’s disease and other neurodegenerative disorders—memantine, a new hope , Pharmacological Research , 51 , 1 , (1) , .

Debby Van Dam, Dorothee Abramowski, Matthias Staufenbiel and Peter Paul De Deyn , Symptomatic effect of donepezil, rivastigmine, galantamine and memantine on cognitive deficits in the APP23 model , Psychopharmacology , 10.1007/s00213-004-2132-z , 180 , 1 , (177-190) , .

Jose L. Molinuevo, Vicente Garcia-Gil and Amparo Villar , Memantine: An antiglutamatergic option for dementia , American Journal of Alzheimer's Disease & Other Dementiasr , 19 , 1 , (10) , .

Gabriele Losi, Giulia Puia, Daniela Braghiroli and Mario Baraldi , IDRA-21, a positive AMPA receptor modulator, inhibits synaptic and extrasynaptic NMDA receptor mediated events in cultured cerebellar granule cells , Neuropharmacology , 46 , 8 , (1105) , .

Hans J. Möbius , Memantine: update on the current evidence , International Journal of Geriatric Psychiatry , 18 , S1 , (S47-S54) , .

Wojciech Danysz and Chris G. Parsons , The NMDA receptor antagonist memantine as a symptomatological and neuroprotective treatment for Alzheimer's disease: preclinical evidence , International Journal of Geriatric Psychiatry , 18 , S1 , (S23-S32) , .

Michael A. Rogawski and Gary L. Wenk , The Neuropharmacological Basis for the Use of Memantine in the Treatment of Alzheimer's Disease , CNS Drug Reviews , 9 , 3 , (275-308) , .

Desiree M. Villarreal, Viet Do, Evelyn Haddad and Brian E. Derrick , NMDA receptor antagonists sustain LTP and spatial memory: active processes mediate LTP decay , Nature Neuroscience , 5 , 1 , (48) , .

Jean-Marc Orgogozo, Anne-Sophie Rigaud, Albrecht Stöffler, Hans-Jorgen Möbius and Françoise Forette , Efficacy and Safety of Memantine in Patients With Mild to Moderate Vascular Dementia , Stroke , 10.1161/01.STR.0000020094.08790.49 , 33 , 7 , (1834-1839) , .

G. Wilcock, H.J. M??bius and A. St??ffler , A double-blind, placebo-controlled multicentre study of memantine in mild to moderate vascular dementia (MMM500) , International Clinical Psychopharmacology , 10.1097/00004850-200211000-00005 , 17 , 6 , (297-305) , .

Chris G Parsons , NMDA receptors as targets for drug action in neuropathic pain , European Journal of Pharmacology , 429 , 1-3 , (71) , .

Rudi D’Hooge and Peter P De Deyn , Applications of the Morris water maze in the study of learning and memory , Brain Research Reviews , 36 , 1 , (60) , .

Kewal K Jain , Evaluation of memantine for neuroprotection in dementia , Expert Opinion on Investigational Drugs , 9 , 6 , (1397) , .

Gary L. Wenk, Guenter Quack, Hans-Joerg Moebius and Wojciech Danysz , No interaction of memantine with acetylcholinesterase inhibitors approved for clinical use , Life Sciences , 66 , 12 , (1079) , .

Jessica A. Cardin and Ted Abel , Memory suppressor genes: Enhancing the relationship between synaptic plasticity and memory storage , Journal of Neuroscience Research , 58 , 1 , (10-23) , .

Ramón Cacabelos, Masatoshi Takeda and Bengt Winblad , The glutamatergic system and neurodegeneration in dementia: preventive strategies in Alzheimer's disease , International Journal of Geriatric Psychiatry , 14 , 1 , (3-47) , .

Tadeusz Frankiewicz and Chris G Parsons , Memantine restores long term potentiation impaired by tonic N-methyl-d-aspartate (NMDA) receptor activation following reduction of Mg2+ In hippocampal slices , Neuropharmacology , 38 , 9 , (1253) , .

Thomas C Foster , Involvement of hippocampal synaptic plasticity in age-related memory decline , Brain Research Reviews , 30 , 3 , (236) , .

C.G. Parsons, W. Danysz and G. Quack , Memantine is a clinically well tolerated N-methyl-d-aspartate (NMDA) receptor antagonist—a review of preclinical data , Neuropharmacology , 38 , 6 , (735) , .

H.-S.V Chen, Y.F Wang, P.V Rayudu, P Edgecomb, J.C Neill, M.M Segal, S.A Lipton and F.E Jensen , Neuroprotective concentrations of the N-methyl-D-aspartate open-channel blocker memantine are effective without cytoplasmic vacuolation following post-ischemic administration and do not block maze learning or long-term potentiation , Neuroscience , 86 , 4 , (1121) , .

Ole A. Andreassen, Trond O. Aamo and Hugo A. Jørgensen , Inhibition by memantine of the development of persistent oral dyskinesias induced by long‐term haloperidol treatment of rats , British Journal of Pharmacology , 119 , 4 , (751-757) , .