Kansas wide receiver/running back Tony Pierson suffered a concussion at the end of a spectacular 39-yard catch-and-run against Texas Tech on Saturday.

Jayhawks head coach Charlie Weis said it was reasonable to expect Pierson to miss several games because of the injury.

"His head hurt, so I'm sure that he took a good knock on the head and has a concussion," Weis said. "He'll probably miss some substantial time would be my guess."

Pierson had a team-high six receptions for 118 yards, capped by the short swing pass where he shook a tackle, reversed field only to cut back and into the open field for a long gain.

<a href="http://msn.foxsports.com/video?videoid=3a6f785e-df25-4c63-a85d-f82eb66ae50e&amp;src=v5:embed:syndication:&amp;from=shareembed-syndication" target="_new" title="Pierson's 39-yard run up the sideline">Video: Pierson's 39-yard run up the sideline</a>

The former running back has been KU's most dynamic weapon on offense. Pierson has 21 receptions for 327 yards, accounting for 41.9 percent of its aerial output this season. The 5-foot-10, 175-pound junior is also averaging 6.7 yards per carry.

Being without Pierson for any length of time will seriously hinder KU's hopes of winning a Big 12 conference game for the first time since Nov. 2010.

Follow Dan Greenspan on Twitter @DanGreenspan.