Volume 116(8); 2019 Feb 19

Articles from this journal are generally available in PMC after a 6-month delay (embargo); however, the delay may vary at the discretion of the publisher.

This Week in PNAS

In this issue Proc Natl Acad Sci U S A. 116(8): 2777–2778. Published online 2019 Feb 19. doi: 10.1073/iti0819116 PMCID: PMC6386659

Letters

Frequency tagging cannot measure neural tracking of beat or meter Vani G. Rajendran, Jan W. H. Schnupp Proc Natl Acad Sci U S A. 116(8): 2779–2780. Published online 2019 Jan 29. doi: 10.1073/pnas.1820020116 PMCID: PMC6386709

Reply to Rajendran and Schnupp: Frequency tagging is sensitive to the temporal structure of signals Tomas Lenc, Peter E. Keller, Manuel Varlet, Sylvie Nozaradan Proc Natl Acad Sci U S A. 116(8): 2781–2782. Published online 2019 Jan 29. doi: 10.1073/pnas.1820941116 PMCID: PMC6386670

Music training, music aptitude, and speech perception E. Glenn Schellenberg Proc Natl Acad Sci U S A. 116(8): 2783–2784. Published online 2019 Jan 29. doi: 10.1073/pnas.1821109116 PMCID: PMC6386686

Reply to Schellenberg: Is there more to auditory plasticity than meets the ear? Gavin M. Bidelman, Kelsey Mankel Proc Natl Acad Sci U S A. 116(8): 2785–2786. Published online 2019 Jan 29. doi: 10.1073/pnas.1900068116 PMCID: PMC6386652

News Feature

News Feature: Cities serve as testbeds for evolutionary change Carolyn Beans Proc Natl Acad Sci U S A. 116(8): 2787–2790. Published online 2019 Feb 19. doi: 10.1073/pnas.1820852116 PMCID: PMC6386729

Profile

Profile of Eric Rignot Brian Doctrow Proc Natl Acad Sci U S A. 116(8): 2791–2793. Published online 2019 Feb 11. doi: 10.1073/pnas.1821951116 PMCID: PMC6386653

Commentaries

Homogeneous catalysis for the nitrogen fuel cycle Yanming Liu, Thomas J. Meyer Proc Natl Acad Sci U S A. 116(8): 2794–2795. Published online 2019 Feb 8. doi: 10.1073/pnas.1822090116 PMCID: PMC6386706

Integrating morphology and phylogenomics supports a terrestrial origin of insect flight Prashant P. Sharma Proc Natl Acad Sci U S A. 116(8): 2796–2798. Published online 2019 Jan 29. doi: 10.1073/pnas.1822087116 PMCID: PMC6386717

Squid genomes in a bacterial world Thomas C. G. Bosch Proc Natl Acad Sci U S A. 116(8): 2799–2801. Published online 2019 Jan 23. doi: 10.1073/pnas.1822166116 PMCID: PMC6386672

The future of influenza forecasts Cécile Viboud, Alessandro Vespignani Proc Natl Acad Sci U S A. 116(8): 2802–2804. Published online 2019 Feb 8. doi: 10.1073/pnas.1822167116 PMCID: PMC6386701

PNAS Plus

Harmonic dynamics of the abelian sandpile Moritz Lang, Mikhail Shkolnikov Proc Natl Acad Sci U S A. 116(8): 2821–2830. Published online 2019 Feb 6. doi: 10.1073/pnas.1812015116 PMCID: PMC6386721

Visualizing the iron atom exchange front in the Fe(II)-catalyzed recrystallization of goethite by atom probe tomography Sandra D. Taylor, Jia Liu, Xin Zhang, Bruce W. Arey, Libor Kovarik, Daniel K. Schreiber, Daniel E. Perea, Kevin M. Rosso Proc Natl Acad Sci U S A. 116(8): 2866–2874. Published online 2019 Feb 7. doi: 10.1073/pnas.1816620116 PMCID: PMC6386708

Universality of local weak interactions and its application for interferometric alignment Jan Dziewior, Lukas Knips, Demitry Farfurnik, Katharina Senkalla, Nimrod Benshalom, Jonathan Efroni, Jasmin Meinecke, Shimshon Bar-Ad, Harald Weinfurter, Lev Vaidman Proc Natl Acad Sci U S A. 116(8): 2881–2890. Published online 2019 Feb 5. doi: 10.1073/pnas.1812970116 PMCID: PMC6386691

Structure–function characterization of an insecticidal protein GNIP1Aa, a member of an MACPF and β-tripod families Jelena Zaitseva, Daniel Vaknin, Christian Krebs, James Doroghazi, Sara L. Milam, Deepa Balasubramanian, Nicholas B. Duck, Joerg Freigang Proc Natl Acad Sci U S A. 116(8): 2897–2906. Published online 2019 Feb 6. doi: 10.1073/pnas.1815547116 PMCID: PMC6386698

Magnesium-sensitive upstream ORF controls PRL phosphatase expression to mediate energy metabolism Serge Hardy, Elie Kostantin, Shan Jin Wang, Tzvetena Hristova, Gabriela Galicia-Vázquez, Pavel V. Baranov, Jerry Pelletier, Michel L. Tremblay Proc Natl Acad Sci U S A. 116(8): 2925–2934. Published online 2019 Feb 4. doi: 10.1073/pnas.1815361116 PMCID: PMC6386685

Molecular basis for AU-rich element recognition and dimerization by the HuR C-terminal RRM Nina Ripin, Julien Boudet, Malgorzata M. Duszczyk, Alexandra Hinniger, Michael Faller, Miroslav Krepl, Abhilash Gadi, Robert J. Schneider, Jiří Šponer, Nicole C. Meisner-Kober, Frédéric H.-T. Allain Proc Natl Acad Sci U S A. 116(8): 2935–2944. Published online 2019 Feb 4. doi: 10.1073/pnas.1808696116 PMCID: PMC6386705

Structural basis for antiarrhythmic drug interactions with the human cardiac sodium channel Phuong T. Nguyen, Kevin R. DeMarco, Igor Vorobyov, Colleen E. Clancy, Vladimir Yarov-Yarovoy Proc Natl Acad Sci U S A. 116(8): 2945–2954. Published online 2019 Feb 6. doi: 10.1073/pnas.1817446116 PMCID: PMC6386684

ERK2 regulates epithelial-to-mesenchymal plasticity through DOCK10-dependent Rac1/FoxO1 activation Sejeong Shin, Gwen R. Buel, Michal J. Nagiec, Min-Joon Han, Philippe P. Roux, John Blenis, Sang-Oh Yoon Proc Natl Acad Sci U S A. 116(8): 2967–2976. Published online 2019 Feb 6. doi: 10.1073/pnas.1811923116 PMCID: PMC6386703

Abnormal glycogen storage in tuberous sclerosis complex caused by impairment of mTORC1-dependent and -independent signaling pathways Rituraj Pal, Yan Xiong, Marco Sardiello Proc Natl Acad Sci U S A. 116(8): 2977–2986. Published online 2019 Feb 6. doi: 10.1073/pnas.1812943116 PMCID: PMC6386676

Canonical Wnt is inhibited by targeting one-carbon metabolism through methotrexate or methionine deprivation Lauren V. Albrecht, Maggie H. Bui, Edward M. De Robertis Proc Natl Acad Sci U S A. 116(8): 2987–2995. Published online 2019 Jan 24. doi: 10.1073/pnas.1820161116 PMCID: PMC6386671

Chaperone-mediated autophagy is involved in the execution of ferroptosis Zheming Wu, Yang Geng, Xiaojuan Lu, Yuying Shi, Guowei Wu, Mengmeng Zhang, Bing Shan, Heling Pan, Junying Yuan Proc Natl Acad Sci U S A. 116(8): 2996–3005. Published online 2019 Feb 4. doi: 10.1073/pnas.1819728116 PMCID: PMC6386716

SraL sRNA interaction regulates the terminator by preventing premature transcription termination of rho mRNA Inês Jesus Silva, Susana Barahona, Alex Eyraud, David Lalaouna, Nara Figueroa-Bossi, Eric Massé, Cecília Maria Arraiano Proc Natl Acad Sci U S A. 116(8): 3042–3051. Published online 2019 Feb 4. doi: 10.1073/pnas.1811589116 PMCID: PMC6386699

Relapse-associated AURKB blunts the glucocorticoid sensitivity of B cell acute lymphoblastic leukemia Coralie Poulard, Hye Na Kim, Mimi Fang, Karina Kruth, Celine Gagnieux, Daniel S. Gerke, Deepa Bhojwani, Yong-Mi Kim, Martin Kampmann, Michael R. Stallcup, Miles A. Pufall Proc Natl Acad Sci U S A. 116(8): 3052–3061. Published online 2019 Feb 7. doi: 10.1073/pnas.1816254116 PMCID: PMC6386662

Defining the impact of mutation accumulation on replicative lifespan in yeast using cancer-associated mutator phenotypes Mitchell B. Lee, Ian T. Dowsett, Daniel T. Carr, Brian M. Wasko, Sarah G. Stanton, Michael S. Chung, Niloufar Ghodsian, Anna Bode, Michael G. Kiflezghi, Priya A. Uppal, Katherine A. Grayden, Yordanos C. Elala, Thao T. Tang, Ngoc H. B. Tran, Thu H. B. Tran, Anh B. Diep, Michael Hope, Daniel E. L. Promislow, Scott R. Kennedy, Matt Kaeberlein, Alan J. Herr Proc Natl Acad Sci U S A. 116(8): 3062–3071. Published online 2019 Feb 4. doi: 10.1073/pnas.1815966116 PMCID: PMC6386679

Humanized UGT2 and CYP3A transchromosomic rats for improved prediction of human drug metabolism Yasuhiro Kazuki, Kaoru Kobayashi, Masumi Hirabayashi, Satoshi Abe, Naoyo Kajitani, Kanako Kazuki, Shoko Takehara, Masato Takiguchi, Daisuke Satoh, Jiro Kuze, Tetsushi Sakuma, Takehito Kaneko, Tomoji Mashimo, Minori Osamura, Mari Hashimoto, Riko Wakatsuki, Rika Hirashima, Ryoichi Fujiwara, Tsuneo Deguchi, Atsushi Kurihara, Yasuko Tsukazaki, Naoto Senda, Takashi Yamamoto, Nico Scheer, Mitsuo Oshimura Proc Natl Acad Sci U S A. 116(8): 3072–3081. Published online 2019 Feb 4. doi: 10.1073/pnas.1808255116 PMCID: PMC6386724

Experimental evolutionary studies on the genetic autonomy of the cytoplasmic genome “plasmon” in the Triticum (wheat)–Aegilops complex Koichiro Tsunewaki, Naoki Mori, Shigeo Takumi Proc Natl Acad Sci U S A. 116(8): 3082–3090. Published online 2019 Feb 6. doi: 10.1073/pnas.1817037116 PMCID: PMC6386668

Comparative transcriptomics method to infer gene coexpression networks and its applications to maize and rice leaf transcriptomes Yao-Ming Chang, Hsin-Hung Lin, Wen-Yu Liu, Chun-Ping Yu, Hsiang-June Chen, Putu Puja Wartini, Yi-Ying Kao, Yeh-Hua Wu, Jinn-Jy Lin, Mei-Yeh Jade Lu, Shih-Long Tu, Shu-Hsing Wu, Shin-Han Shiu, Maurice S. B. Ku, Wen-Hsiung Li Proc Natl Acad Sci U S A. 116(8): 3091–3099. Published online 2019 Feb 4. doi: 10.1073/pnas.1817621116 PMCID: PMC6386681

High ambient temperature dampens adaptive immune responses to influenza A virus infection Miyu Moriyama, Takeshi Ichinohe Proc Natl Acad Sci U S A. 116(8): 3118–3125. Published online 2019 Feb 4. doi: 10.1073/pnas.1815029116 PMCID: PMC6386664

DGAT1 inhibits retinol-dependent regulatory T cell formation and mediates autoimmune encephalomyelitis Kareem L. Graham, Bonnie J. Werner, Kimberly M. Moyer, Alycia K. Patton, Charles R. Krois, Hong Sik Yoo, Maria Tverskoy, Melissa LaJevic, Joseph L. Napoli, Raymond A. Sobel, Brian A. Zabel, Eugene C. Butcher Proc Natl Acad Sci U S A. 116(8): 3126–3135. Published online 2019 Feb 4. doi: 10.1073/pnas.1817669116 PMCID: PMC6386656

Breaking tolerance with engineered class I antigen-presenting molecules Christopher A. Parks, Kalli R. Henning, Kevin D. Pavelko, Michael J. Hansen, Virginia P. Van Keulen, Brendan K. Reed, Jennifer D. Stone, Adam G. Schrum, Diana Gil, David M. Kranz, Andrew J. Bordner, Michael A. Barry, Larry R. Pease Proc Natl Acad Sci U S A. 116(8): 3136–3145. Published online 2019 Feb 6. doi: 10.1073/pnas.1807465116 PMCID: PMC6386718

A collaborative multiyear, multimodel assessment of seasonal influenza forecasting in the United States Nicholas G. Reich, Logan C. Brooks, Spencer J. Fox, Sasikiran Kandula, Craig J. McGowan, Evan Moore, Dave Osthus, Evan L. Ray, Abhinav Tushar, Teresa K. Yamana, Matthew Biggerstaff, Michael A. Johansson, Roni Rosenfeld, Jeffrey Shaman Proc Natl Acad Sci U S A. 116(8): 3146–3154. Published online 2019 Jan 15. doi: 10.1073/pnas.1812594116 PMCID: PMC6386665

Increased gene copy number of DEFA1/DEFA3 worsens sepsis by inducing endothelial pyroptosis QiXing Chen, Yang Yang, JinChao Hou, Qiang Shu, YiXuan Yin, WeiTao Fu, Feng Han, TingJun Hou, CongLi Zeng, Elizabeta Nemeth, Rose Linzmeier, Tomas Ganz, XiangMing Fang Proc Natl Acad Sci U S A. 116(8): 3161–3170. Published online 2019 Feb 4. doi: 10.1073/pnas.1812947116 PMCID: PMC6386704

Comparative 3D genome organization in apicomplexan parasites Evelien M. Bunnik, Aarthi Venkat, Jianlin Shao, Kathryn E. McGovern, Gayani Batugedara, Danielle Worth, Jacques Prudhomme, Stacey A. Lapp, Chiara Andolina, Leila S. Ross, Lauren Lawres, Declan Brady, Photini Sinnis, Francois Nosten, David A. Fidock, Emma H. Wilson, Rita Tewari, Mary R. Galinski, Choukri Ben Mamoun, Ferhat Ay, Karine G. Le Roch Proc Natl Acad Sci U S A. 116(8): 3183–3192. Published online 2019 Feb 5. doi: 10.1073/pnas.1810815116 PMCID: PMC6386730

Intercellular cooperation in a fungal plant pathogen facilitates host colonization Rémi Peyraud, Malick Mbengue, Adelin Barbacci, Sylvain Raffaele Proc Natl Acad Sci U S A. 116(8): 3193–3201. Published online 2019 Feb 6. doi: 10.1073/pnas.1811267116 PMCID: PMC6386666

The Mycobacterium tuberculosis Pup-proteasome system regulates nitrate metabolism through an essential protein quality control pathway Samuel H. Becker, Jordan B. Jastrab, Avantika Dhabaria, Catherine T. Chaton, Jeffrey S. Rush, Konstantin V. Korotkov, Beatrix Ueberheide, K. Heran Darwin Proc Natl Acad Sci U S A. 116(8): 3202–3210. Published online 2019 Feb 5. doi: 10.1073/pnas.1819468116 PMCID: PMC6386731

Movement dynamics of divisome proteins and PBP2x:FtsW in cells of Streptococcus pneumoniae Amilcar J. Perez, Yann Cesbron, Sidney L. Shaw, Jesus Bazan Villicana, Ho-Ching T. Tsui, Michael J. Boersma, Ziyun A. Ye, Yanina Tovpeko, Cees Dekker, Seamus Holden, Malcolm E. Winkler Proc Natl Acad Sci U S A. 116(8): 3211–3220. Published online 2019 Feb 4. doi: 10.1073/pnas.1816018116 PMCID: PMC6386697

Legionella pneumophila translocated translation inhibitors are required for bacterial-induced host cell cycle arrest Asaf Sol, Erion Lipo, Dennise A. de Jesús-Díaz, Connor Murphy, Mildred Devereux, Ralph R. Isberg Proc Natl Acad Sci U S A. 116(8): 3221–3228. Published online 2019 Feb 4. doi: 10.1073/pnas.1820093116 PMCID: PMC6386690

CD4 receptor diversity in chimpanzees protects against SIV infection Frederic Bibollet-Ruche, Ronnie M. Russell, Weimin Liu, Guillaume B. E. Stewart-Jones, Scott Sherrill-Mix, Yingying Li, Gerald H. Learn, Andrew G. Smith, Marcos V. P. Gondim, Lindsey J. Plenderleith, Julie M. Decker, Juliet L. Easlick, Katherine S. Wetzel, Ronald G. Collman, Shilei Ding, Andrés Finzi, Ahidjo Ayouba, Martine Peeters, Fabian H. Leendertz, Joost van Schijndel, Annemarie Goedmakers, Els Ton, Christophe Boesch, Hjalmar Kuehl, Mimi Arandjelovic, Paula Dieguez, Mizuki Murai, Christelle Colin, Kathelijne Koops, Sheri Speede, Mary K. Gonder, Martin N. Muller, Crickette M. Sanz, David B. Morgan, Rebecca Atencia, Debby Cox, Alex K. Piel, Fiona A. Stewart, Jean-Bosco N. Ndjango, Deus Mjungu, Elizabeth V. Lonsdorf, Anne E. Pusey, Peter D. Kwong, Paul M. Sharp, George M. Shaw, Beatrice H. Hahn Proc Natl Acad Sci U S A. 116(8): 3229–3238. Published online 2019 Feb 4. doi: 10.1073/pnas.1821197116 PMCID: PMC6386711

High-dimensional representation of texture in somatosensory cortex of primates Justin D. Lieber, Sliman J. Bensmaia Proc Natl Acad Sci U S A. 116(8): 3268–3277. Published online 2019 Feb 4. doi: 10.1073/pnas.1818501116 PMCID: PMC6386651

Inositol hexakisphosphate kinase 3 promotes focal adhesion turnover via interactions with dynein intermediate chain 2 Tomas Rojas, Weiwei Cheng, Zhe Gao, Xiaoqi Liu, Yakun Wang, Adarsha P. Malla, Alfred C. Chin, Lewis H. Romer, Solomon H. Snyder, Chenglai Fu Proc Natl Acad Sci U S A. 116(8): 3278–3287. Published online 2019 Feb 4. doi: 10.1073/pnas.1817001116 PMCID: PMC6386689

Regulatory cascade involving transcriptional and N-end rule pathways in rice under submergence Chih-Cheng Lin, Ya-Ting Chao, Wan-Chieh Chen, Hsiu-Yin Ho, Mei-Yi Chou, Ya-Ru Li, Yu-Lin Wu, Hung-An Yang, Hsiang Hsieh, Choun-Sea Lin, Fu-Hui Wu, Shu-Jen Chou, Hao-Chung Jen, Yung-Hsiang Huang, Deli Irene, Wen-Jin Wu, Jian-Li Wu, Daniel J. Gibbs, Meng-Chiao Ho, Ming-Che Shih Proc Natl Acad Sci U S A. 116(8): 3300–3309. Published online 2019 Feb 5. doi: 10.1073/pnas.1818507116 PMCID: PMC6386710

Genome-wide colocalization of RNA–DNA interactions and fusion RNA pairs Zhangming Yan, Norman Huang, Weixin Wu, Weizhong Chen, Yiqun Jiang, Jingyao Chen, Xuerui Huang, Xingzhao Wen, Jie Xu, Qiushi Jin, Kang Zhang, Zhen Chen, Shu Chien, Sheng Zhong Proc Natl Acad Sci U S A. 116(8): 3328–3337. Published online 2019 Feb 4. doi: 10.1073/pnas.1819788116 PMCID: PMC6386723

Perspective

Interpreting contemporary trends in atmospheric methane Alexander J. Turner, Christian Frankenberg, Eric A. Kort Proc Natl Acad Sci U S A. 116(8): 2805–2813. Published online 2019 Feb 7. doi: 10.1073/pnas.1814297116 PMCID: PMC6386658

Physical Sciences

Applied Mathematics

Harmonic dynamics of the abelian sandpile Moritz Lang, Mikhail Shkolnikov Proc Natl Acad Sci U S A. 116(8): 2821–2830. Published online 2019 Feb 6. doi: 10.1073/pnas.1812015116 PMCID: PMC6386721

Applied Physical Sciences

Zintl-phase Eu 2 ZnSb 2 : A promising thermoelectric material with ultralow thermal conductivity Chen Chen, Wenhua Xue, Shan Li, Zongwei Zhang, Xiaofang Li, Xinyu Wang, Yijie Liu, Jiehe Sui, Xingjun Liu, Feng Cao, Zhifeng Ren, Ching-Wu Chu, Yumei Wang, Qian Zhang Proc Natl Acad Sci U S A. 116(8): 2831–2836. Published online 2019 Feb 4. doi: 10.1073/pnas.1819157116 PMCID: PMC6386660

Biophysics and Computational Biology

Froghoppers jump from smooth plant surfaces by piercing them with sharp spines Hanns Hagen Goetzke, Jonathan G. Pattrick, Walter Federle Proc Natl Acad Sci U S A. 116(8): 3012–3017. Published online 2019 Feb 4. doi: 10.1073/pnas.1814183116 PMCID: PMC6386693

Chemistry

Homogeneous catalysis for the nitrogen fuel cycle Yanming Liu, Thomas J. Meyer Proc Natl Acad Sci U S A. 116(8): 2794–2795. Published online 2019 Feb 8. doi: 10.1073/pnas.1822090116 PMCID: PMC6386706

Design–functionality relationships for adhesion/growth-regulatory galectins Anna-Kristin Ludwig, Malwina Michalak, Qi Xiao, Ulrich Gilles, Francisco J. Medrano, Hanyue Ma, Forrest G. FitzGerald, William D. Hasley, Adriel Melendez-Davila, Matthew Liu, Khosrow Rahimi, Nina Yu Kostina, Cesar Rodriguez-Emmenegger, Martin Möller, Ingo Lindner, Herbert Kaltner, Mare Cudic, Dietmar Reusch, Jürgen Kopitz, Antonio Romero, Stefan Oscarson, Michael L. Klein, Hans-Joachim Gabius, Virgil Percec Proc Natl Acad Sci U S A. 116(8): 2837–2842. Published online 2019 Feb 4. doi: 10.1073/pnas.1813515116 PMCID: PMC6386680

Consecutive feedback-driven constitutional dynamic networks Liang Yue, Shan Wang, Verena Wulf, Sivan Lilienthal, Françoise Remacle, R. D. Levine, Itamar Willner Proc Natl Acad Sci U S A. 116(8): 2843–2848. Published online 2019 Feb 6. doi: 10.1073/pnas.1816670116 PMCID: PMC6386722

Homogeneous electrocatalytic oxidation of ammonia to N 2 under mild conditions Faezeh Habibzadeh, Susanne L. Miller, Thomas W. Hamann, Milton R. Smith, III Proc Natl Acad Sci U S A. 116(8): 2849–2853. Published online 2019 Jan 17. doi: 10.1073/pnas.1813368116 PMCID: PMC6386726

Resonant inelastic X-ray scattering determination of the electronic structure of oxyhemoglobin and its model complex James J. Yan, Thomas Kroll, Michael L. Baker, Samuel A. Wilson, Richard Decréau, Marcus Lundberg, Dimosthenis Sokaras, Pieter Glatzel, Britt Hedman, Keith O. Hodgson, Edward I. Solomon Proc Natl Acad Sci U S A. 116(8): 2854–2859. Published online 2019 Feb 4. doi: 10.1073/pnas.1815981116 PMCID: PMC6386657

Earth, Atmospheric, and Planetary Sciences

Metabolic preference of nitrate over oxygen as an electron acceptor in foraminifera from the Peruvian oxygen minimum zone Nicolaas Glock, Alexandra-Sophie Roy, Dennis Romero, Tanita Wein, Julia Weissenbach, Niels Peter Revsbech, Signe Høgslund, David Clemens, Stefan Sommer, Tal Dagan Proc Natl Acad Sci U S A. 116(8): 2860–2865. Published online 2019 Feb 6. doi: 10.1073/pnas.1813887116 PMCID: PMC6386669

Environmental Sciences

News Feature: Cities serve as testbeds for evolutionary change Carolyn Beans Proc Natl Acad Sci U S A. 116(8): 2787–2790. Published online 2019 Feb 19. doi: 10.1073/pnas.1820852116 PMCID: PMC6386729

Visualizing the iron atom exchange front in the Fe(II)-catalyzed recrystallization of goethite by atom probe tomography Sandra D. Taylor, Jia Liu, Xin Zhang, Bruce W. Arey, Libor Kovarik, Daniel K. Schreiber, Daniel E. Perea, Kevin M. Rosso Proc Natl Acad Sci U S A. 116(8): 2866–2874. Published online 2019 Feb 7. doi: 10.1073/pnas.1816620116 PMCID: PMC6386708

Physics

Structural hierarchy confers error tolerance in biological materials Jonathan A. Michel, Peter J. Yunker Proc Natl Acad Sci U S A. 116(8): 2875–2880. Published online 2019 Feb 5. doi: 10.1073/pnas.1813801116 PMCID: PMC6386677

Universality of local weak interactions and its application for interferometric alignment Jan Dziewior, Lukas Knips, Demitry Farfurnik, Katharina Senkalla, Nimrod Benshalom, Jonathan Efroni, Jasmin Meinecke, Shimshon Bar-Ad, Harald Weinfurter, Lev Vaidman Proc Natl Acad Sci U S A. 116(8): 2881–2890. Published online 2019 Feb 5. doi: 10.1073/pnas.1812970116 PMCID: PMC6386691

Statistics

The future of influenza forecasts Cécile Viboud, Alessandro Vespignani Proc Natl Acad Sci U S A. 116(8): 2802–2804. Published online 2019 Feb 8. doi: 10.1073/pnas.1822167116 PMCID: PMC6386701

A collaborative multiyear, multimodel assessment of seasonal influenza forecasting in the United States Nicholas G. Reich, Logan C. Brooks, Spencer J. Fox, Sasikiran Kandula, Craig J. McGowan, Evan Moore, Dave Osthus, Evan L. Ray, Abhinav Tushar, Teresa K. Yamana, Matthew Biggerstaff, Michael A. Johansson, Roni Rosenfeld, Jeffrey Shaman Proc Natl Acad Sci U S A. 116(8): 3146–3154. Published online 2019 Jan 15. doi: 10.1073/pnas.1812594116 PMCID: PMC6386665

Social Science

Social Science

Stalls in Africa’s fertility decline partly result from disruptions in female education Endale Kebede, Anne Goujon, Wolfgang Lutz Proc Natl Acad Sci U S A. 116(8): 2891–2896. Published online 2019 Feb 4. doi: 10.1073/pnas.1717288116 PMCID: PMC6386713

Biological Sciences

Agricultural Sciences

Structure–function characterization of an insecticidal protein GNIP1Aa, a member of an MACPF and β-tripod families Jelena Zaitseva, Daniel Vaknin, Christian Krebs, James Doroghazi, Sara L. Milam, Deepa Balasubramanian, Nicholas B. Duck, Joerg Freigang Proc Natl Acad Sci U S A. 116(8): 2897–2906. Published online 2019 Feb 6. doi: 10.1073/pnas.1815547116 PMCID: PMC6386698

Biochemistry

Mass spectrometry: From plasma proteins to mitochondrial membranes Carol V. Robinson Proc Natl Acad Sci U S A. 116(8): 2814–2820. Published online 2019 Feb 4. doi: 10.1073/pnas.1820450116 PMCID: PMC6386728

Phosphorylation-mediated activation of mouse Xkr8 scramblase for phosphatidylserine exposure Takaharu Sakuragi, Hidetaka Kosako, Shigekazu Nagata Proc Natl Acad Sci U S A. 116(8): 2907–2912. Published online 2019 Feb 4. doi: 10.1073/pnas.1820499116 PMCID: PMC6386700

Drosophila melanogaster nonribosomal peptide synthetase Ebony encodes an atypical condensation domain Thierry Izoré, Julien Tailhades, Mathias Henning Hansen, Joe A. Kaczmarski, Colin J. Jackson, Max J. Cryle Proc Natl Acad Sci U S A. 116(8): 2913–2918. Published online 2019 Jan 31. doi: 10.1073/pnas.1811194116 PMCID: PMC6386674

Structural insights into FTO’s catalytic mechanism for the demethylation of multiple RNA substrates Xiao Zhang, Lian-Huan Wei, Yuxin Wang, Yu Xiao, Jun Liu, Wei Zhang, Ning Yan, Gubu Amu, Xinjing Tang, Liang Zhang, Guifang Jia Proc Natl Acad Sci U S A. 116(8): 2919–2924. Published online 2019 Feb 4. doi: 10.1073/pnas.1820574116 PMCID: PMC6386707

Magnesium-sensitive upstream ORF controls PRL phosphatase expression to mediate energy metabolism Serge Hardy, Elie Kostantin, Shan Jin Wang, Tzvetena Hristova, Gabriela Galicia-Vázquez, Pavel V. Baranov, Jerry Pelletier, Michel L. Tremblay Proc Natl Acad Sci U S A. 116(8): 2925–2934. Published online 2019 Feb 4. doi: 10.1073/pnas.1815361116 PMCID: PMC6386685

Biophysics and Computational Biology

Structural hierarchy confers error tolerance in biological materials Jonathan A. Michel, Peter J. Yunker Proc Natl Acad Sci U S A. 116(8): 2875–2880. Published online 2019 Feb 5. doi: 10.1073/pnas.1813801116 PMCID: PMC6386677

Molecular basis for AU-rich element recognition and dimerization by the HuR C-terminal RRM Nina Ripin, Julien Boudet, Malgorzata M. Duszczyk, Alexandra Hinniger, Michael Faller, Miroslav Krepl, Abhilash Gadi, Robert J. Schneider, Jiří Šponer, Nicole C. Meisner-Kober, Frédéric H.-T. Allain Proc Natl Acad Sci U S A. 116(8): 2935–2944. Published online 2019 Feb 4. doi: 10.1073/pnas.1808696116 PMCID: PMC6386705

Structural basis for antiarrhythmic drug interactions with the human cardiac sodium channel Phuong T. Nguyen, Kevin R. DeMarco, Igor Vorobyov, Colleen E. Clancy, Vladimir Yarov-Yarovoy Proc Natl Acad Sci U S A. 116(8): 2945–2954. Published online 2019 Feb 6. doi: 10.1073/pnas.1817446116 PMCID: PMC6386684

Cell Biology

Mature vessel networks in engineered tissue promote graft–host anastomosis and prevent graft thrombosis Shahar Ben-Shaul, Shira Landau, Uri Merdler, Shulamit Levenberg Proc Natl Acad Sci U S A. 116(8): 2955–2960. Published online 2019 Feb 4. doi: 10.1073/pnas.1814238116 PMCID: PMC6386696

MGMT-activated DUB3 stabilizes MCL1 and drives chemoresistance in ovarian cancer Xiaowei Wu, Qingyu Luo, Pengfei Zhao, Wan Chang, Yating Wang, Tong Shu, Fang Ding, Bin Li, Zhihua Liu Proc Natl Acad Sci U S A. 116(8): 2961–2966. Published online 2019 Feb 4. doi: 10.1073/pnas.1814742116 PMCID: PMC6386650

ERK2 regulates epithelial-to-mesenchymal plasticity through DOCK10-dependent Rac1/FoxO1 activation Sejeong Shin, Gwen R. Buel, Michal J. Nagiec, Min-Joon Han, Philippe P. Roux, John Blenis, Sang-Oh Yoon Proc Natl Acad Sci U S A. 116(8): 2967–2976. Published online 2019 Feb 6. doi: 10.1073/pnas.1811923116 PMCID: PMC6386703

Abnormal glycogen storage in tuberous sclerosis complex caused by impairment of mTORC1-dependent and -independent signaling pathways Rituraj Pal, Yan Xiong, Marco Sardiello Proc Natl Acad Sci U S A. 116(8): 2977–2986. Published online 2019 Feb 6. doi: 10.1073/pnas.1812943116 PMCID: PMC6386676

Canonical Wnt is inhibited by targeting one-carbon metabolism through methotrexate or methionine deprivation Lauren V. Albrecht, Maggie H. Bui, Edward M. De Robertis Proc Natl Acad Sci U S A. 116(8): 2987–2995. Published online 2019 Jan 24. doi: 10.1073/pnas.1820161116 PMCID: PMC6386671

Chaperone-mediated autophagy is involved in the execution of ferroptosis Zheming Wu, Yang Geng, Xiaojuan Lu, Yuying Shi, Guowei Wu, Mengmeng Zhang, Bing Shan, Heling Pan, Junying Yuan Proc Natl Acad Sci U S A. 116(8): 2996–3005. Published online 2019 Feb 4. doi: 10.1073/pnas.1819728116 PMCID: PMC6386716

Ecology

Monarch butterfly and milkweed declines substantially predate the use of genetically modified crops J. H. Boyle, H. J. Dalgleish, J. R. Puzey Proc Natl Acad Sci U S A. 116(8): 3006–3011. Published online 2019 Feb 5. doi: 10.1073/pnas.1811437116 PMCID: PMC6386695

Evolution

News Feature: Cities serve as testbeds for evolutionary change Carolyn Beans Proc Natl Acad Sci U S A. 116(8): 2787–2790. Published online 2019 Feb 19. doi: 10.1073/pnas.1820852116 PMCID: PMC6386729

Integrating morphology and phylogenomics supports a terrestrial origin of insect flight Prashant P. Sharma Proc Natl Acad Sci U S A. 116(8): 2796–2798. Published online 2019 Jan 29. doi: 10.1073/pnas.1822087116 PMCID: PMC6386717

Squid genomes in a bacterial world Thomas C. G. Bosch Proc Natl Acad Sci U S A. 116(8): 2799–2801. Published online 2019 Jan 23. doi: 10.1073/pnas.1822166116 PMCID: PMC6386672

Froghoppers jump from smooth plant surfaces by piercing them with sharp spines Hanns Hagen Goetzke, Jonathan G. Pattrick, Walter Federle Proc Natl Acad Sci U S A. 116(8): 3012–3017. Published online 2019 Feb 4. doi: 10.1073/pnas.1814183116 PMCID: PMC6386693

The molecular evolution of feathers with direct evidence from fossils Yanhong Pan, Wenxia Zheng, Roger H. Sawyer, Michael W. Pennington, Xiaoting Zheng, Xiaoli Wang, Min Wang, Liang Hu, Jingmai O’Connor, Tao Zhao, Zhiheng Li, Elena R. Schroeter, Feixiang Wu, Xing Xu, Zhonghe Zhou, Mary H. Schweitzer Proc Natl Acad Sci U S A. 116(8): 3018–3023. Published online 2019 Jan 28. doi: 10.1073/pnas.1815703116 PMCID: PMC6386655

Evolutionary history of Polyneoptera and its implications for our understanding of early winged insects Benjamin Wipfler, Harald Letsch, Paul B. Frandsen, Paschalia Kapli, Christoph Mayer, Daniela Bartel, Thomas R. Buckley, Alexander Donath, Janice S. Edgerly-Rooks, Mari Fujita, Shanlin Liu, Ryuichiro Machida, Yuta Mashimo, Bernhard Misof, Oliver Niehuis, Ralph S. Peters, Malte Petersen, Lars Podsiadlowski, Kai Schütte, Shota Shimizu, Toshiki Uchifune, Jeanne Wilbrandt, Evgeny Yan, Xin Zhou, Sabrina Simon Proc Natl Acad Sci U S A. 116(8): 3024–3029. Published online 2019 Jan 14. doi: 10.1073/pnas.1817794116 PMCID: PMC6386694

Symbiotic organs shaped by distinct modes of genome evolution in cephalopods Mahdi Belcaid, Giorgio Casaburi, Sarah J. McAnulty, Hannah Schmidbaur, Andrea M. Suria, Silvia Moriano-Gutierrez, M. Sabrina Pankey, Todd H. Oakley, Natacha Kremer, Eric J. Koch, Andrew J. Collins, Hoan Nguyen, Sai Lek, Irina Goncharenko-Foster, Patrick Minx, Erica Sodergren, George Weinstock, Daniel S. Rokhsar, Margaret McFall-Ngai, Oleg Simakov, Jamie S. Foster, Spencer V. Nyholm Proc Natl Acad Sci U S A. 116(8): 3030–3035. Published online 2019 Jan 11. doi: 10.1073/pnas.1817322116 PMCID: PMC6386654

Convergent gene losses illuminate metabolic and physiological changes in herbivores and carnivores Nikolai Hecker, Virag Sharma, Michael Hiller Proc Natl Acad Sci U S A. 116(8): 3036–3041. Published online 2019 Feb 4. doi: 10.1073/pnas.1818504116 PMCID: PMC6386725

Genetics

SraL sRNA interaction regulates the terminator by preventing premature transcription termination of rho mRNA Inês Jesus Silva, Susana Barahona, Alex Eyraud, David Lalaouna, Nara Figueroa-Bossi, Eric Massé, Cecília Maria Arraiano Proc Natl Acad Sci U S A. 116(8): 3042–3051. Published online 2019 Feb 4. doi: 10.1073/pnas.1811589116 PMCID: PMC6386699

Relapse-associated AURKB blunts the glucocorticoid sensitivity of B cell acute lymphoblastic leukemia Coralie Poulard, Hye Na Kim, Mimi Fang, Karina Kruth, Celine Gagnieux, Daniel S. Gerke, Deepa Bhojwani, Yong-Mi Kim, Martin Kampmann, Michael R. Stallcup, Miles A. Pufall Proc Natl Acad Sci U S A. 116(8): 3052–3061. Published online 2019 Feb 7. doi: 10.1073/pnas.1816254116 PMCID: PMC6386662

Defining the impact of mutation accumulation on replicative lifespan in yeast using cancer-associated mutator phenotypes Mitchell B. Lee, Ian T. Dowsett, Daniel T. Carr, Brian M. Wasko, Sarah G. Stanton, Michael S. Chung, Niloufar Ghodsian, Anna Bode, Michael G. Kiflezghi, Priya A. Uppal, Katherine A. Grayden, Yordanos C. Elala, Thao T. Tang, Ngoc H. B. Tran, Thu H. B. Tran, Anh B. Diep, Michael Hope, Daniel E. L. Promislow, Scott R. Kennedy, Matt Kaeberlein, Alan J. Herr Proc Natl Acad Sci U S A. 116(8): 3062–3071. Published online 2019 Feb 4. doi: 10.1073/pnas.1815966116 PMCID: PMC6386679

Humanized UGT2 and CYP3A transchromosomic rats for improved prediction of human drug metabolism Yasuhiro Kazuki, Kaoru Kobayashi, Masumi Hirabayashi, Satoshi Abe, Naoyo Kajitani, Kanako Kazuki, Shoko Takehara, Masato Takiguchi, Daisuke Satoh, Jiro Kuze, Tetsushi Sakuma, Takehito Kaneko, Tomoji Mashimo, Minori Osamura, Mari Hashimoto, Riko Wakatsuki, Rika Hirashima, Ryoichi Fujiwara, Tsuneo Deguchi, Atsushi Kurihara, Yasuko Tsukazaki, Naoto Senda, Takashi Yamamoto, Nico Scheer, Mitsuo Oshimura Proc Natl Acad Sci U S A. 116(8): 3072–3081. Published online 2019 Feb 4. doi: 10.1073/pnas.1808255116 PMCID: PMC6386724

Experimental evolutionary studies on the genetic autonomy of the cytoplasmic genome “plasmon” in the Triticum (wheat)–Aegilops complex Koichiro Tsunewaki, Naoki Mori, Shigeo Takumi Proc Natl Acad Sci U S A. 116(8): 3082–3090. Published online 2019 Feb 6. doi: 10.1073/pnas.1817037116 PMCID: PMC6386668

Comparative transcriptomics method to infer gene coexpression networks and its applications to maize and rice leaf transcriptomes Yao-Ming Chang, Hsin-Hung Lin, Wen-Yu Liu, Chun-Ping Yu, Hsiang-June Chen, Putu Puja Wartini, Yi-Ying Kao, Yeh-Hua Wu, Jinn-Jy Lin, Mei-Yeh Jade Lu, Shih-Long Tu, Shu-Hsing Wu, Shin-Han Shiu, Maurice S. B. Ku, Wen-Hsiung Li Proc Natl Acad Sci U S A. 116(8): 3091–3099. Published online 2019 Feb 4. doi: 10.1073/pnas.1817621116 PMCID: PMC6386681

Immunology and Inflammation

Second-generation IL-2 receptor-targeted diphtheria fusion toxin exhibits antitumor activity and synergy with anti–PD-1 in melanoma Laurene S. Cheung, Juan Fu, Pankaj Kumar, Amit Kumar, Michael E. Urbanowski, Elizabeth A. Ihms, Sadiya Parveen, C. Korin Bullen, Garrett J. Patrick, Robert Harrison, John R. Murphy, Drew M. Pardoll, William R. Bishai Proc Natl Acad Sci U S A. 116(8): 3100–3105. Published online 2019 Feb 4. doi: 10.1073/pnas.1815087116 PMCID: PMC6386727

IL-27 confers a protumorigenic activity of regulatory T cells via CD39 Young-Jun Park, Heeju Ryu, Garam Choi, Byung-Seok Kim, Eun Sook Hwang, Hun Sik Kim, Yeonseok Chung Proc Natl Acad Sci U S A. 116(8): 3106–3111. Published online 2019 Feb 4. doi: 10.1073/pnas.1810254116 PMCID: PMC6386675

Most viral peptides displayed by class I MHC on infected cells are immunogenic Nathan P. Croft, Stewart A. Smith, Jana Pickering, John Sidney, Bjoern Peters, Pouya Faridi, Matthew J. Witney, Prince Sebastian, Inge E. A. Flesch, Sally L. Heading, Alessandro Sette, Nicole L. La Gruta, Anthony W. Purcell, David C. Tscharke Proc Natl Acad Sci U S A. 116(8): 3112–3117. Published online 2019 Feb 4. doi: 10.1073/pnas.1815239116 PMCID: PMC6386720

High ambient temperature dampens adaptive immune responses to influenza A virus infection Miyu Moriyama, Takeshi Ichinohe Proc Natl Acad Sci U S A. 116(8): 3118–3125. Published online 2019 Feb 4. doi: 10.1073/pnas.1815029116 PMCID: PMC6386664

DGAT1 inhibits retinol-dependent regulatory T cell formation and mediates autoimmune encephalomyelitis Kareem L. Graham, Bonnie J. Werner, Kimberly M. Moyer, Alycia K. Patton, Charles R. Krois, Hong Sik Yoo, Maria Tverskoy, Melissa LaJevic, Joseph L. Napoli, Raymond A. Sobel, Brian A. Zabel, Eugene C. Butcher Proc Natl Acad Sci U S A. 116(8): 3126–3135. Published online 2019 Feb 4. doi: 10.1073/pnas.1817669116 PMCID: PMC6386656

Breaking tolerance with engineered class I antigen-presenting molecules Christopher A. Parks, Kalli R. Henning, Kevin D. Pavelko, Michael J. Hansen, Virginia P. Van Keulen, Brendan K. Reed, Jennifer D. Stone, Adam G. Schrum, Diana Gil, David M. Kranz, Andrew J. Bordner, Michael A. Barry, Larry R. Pease Proc Natl Acad Sci U S A. 116(8): 3136–3145. Published online 2019 Feb 6. doi: 10.1073/pnas.1807465116 PMCID: PMC6386718

Medical Sciences

The future of influenza forecasts Cécile Viboud, Alessandro Vespignani Proc Natl Acad Sci U S A. 116(8): 2802–2804. Published online 2019 Feb 8. doi: 10.1073/pnas.1822167116 PMCID: PMC6386701

A collaborative multiyear, multimodel assessment of seasonal influenza forecasting in the United States Nicholas G. Reich, Logan C. Brooks, Spencer J. Fox, Sasikiran Kandula, Craig J. McGowan, Evan Moore, Dave Osthus, Evan L. Ray, Abhinav Tushar, Teresa K. Yamana, Matthew Biggerstaff, Michael A. Johansson, Roni Rosenfeld, Jeffrey Shaman Proc Natl Acad Sci U S A. 116(8): 3146–3154. Published online 2019 Jan 15. doi: 10.1073/pnas.1812594116 PMCID: PMC6386665

Calcineurin dephosphorylates Kelch-like 3, reversing phosphorylation by angiotensin II and regulating renal electrolyte handling Kenichi Ishizawa, Qin Wang, Jinping Li, Osamu Yamazaki, Yoshifuru Tamura, Yoshihide Fujigaki, Shunya Uchida, Richard P. Lifton, Shigeru Shibata Proc Natl Acad Sci U S A. 116(8): 3155–3160. Published online 2019 Feb 4. doi: 10.1073/pnas.1817281116 PMCID: PMC6386661

Increased gene copy number of DEFA1/DEFA3 worsens sepsis by inducing endothelial pyroptosis QiXing Chen, Yang Yang, JinChao Hou, Qiang Shu, YiXuan Yin, WeiTao Fu, Feng Han, TingJun Hou, CongLi Zeng, Elizabeta Nemeth, Rose Linzmeier, Tomas Ganz, XiangMing Fang Proc Natl Acad Sci U S A. 116(8): 3161–3170. Published online 2019 Feb 4. doi: 10.1073/pnas.1812947116 PMCID: PMC6386704

Microbiology

A glycyl radical enzyme enables hydrogen sulfide production by the human intestinal bacterium Bilophila wadsworthia Spencer C. Peck, Karin Denger, Anna Burrichter, Stephania M. Irwin, Emily P. Balskus, David Schleheck Proc Natl Acad Sci U S A. 116(8): 3171–3176. Published online 2019 Feb 4. doi: 10.1073/pnas.1815661116 PMCID: PMC6386719

DNA helicase RecQ1 regulates mutually exclusive expression of virulence genes in Plasmodium falciparum via heterochromatin alteration Zhou Li, Shigang Yin, Maoxin Sun, Xiu Cheng, Jieqiong Wei, Nicolas Gilbert, Jun Miao, Liwang Cui, Zhenghui Huang, Xueyu Dai, Lubin Jiang Proc Natl Acad Sci U S A. 116(8): 3177–3182. Published online 2019 Feb 6. doi: 10.1073/pnas.1811766116 PMCID: PMC6386683

Comparative 3D genome organization in apicomplexan parasites Evelien M. Bunnik, Aarthi Venkat, Jianlin Shao, Kathryn E. McGovern, Gayani Batugedara, Danielle Worth, Jacques Prudhomme, Stacey A. Lapp, Chiara Andolina, Leila S. Ross, Lauren Lawres, Declan Brady, Photini Sinnis, Francois Nosten, David A. Fidock, Emma H. Wilson, Rita Tewari, Mary R. Galinski, Choukri Ben Mamoun, Ferhat Ay, Karine G. Le Roch Proc Natl Acad Sci U S A. 116(8): 3183–3192. Published online 2019 Feb 5. doi: 10.1073/pnas.1810815116 PMCID: PMC6386730

Intercellular cooperation in a fungal plant pathogen facilitates host colonization Rémi Peyraud, Malick Mbengue, Adelin Barbacci, Sylvain Raffaele Proc Natl Acad Sci U S A. 116(8): 3193–3201. Published online 2019 Feb 6. doi: 10.1073/pnas.1811267116 PMCID: PMC6386666

The Mycobacterium tuberculosis Pup-proteasome system regulates nitrate metabolism through an essential protein quality control pathway Samuel H. Becker, Jordan B. Jastrab, Avantika Dhabaria, Catherine T. Chaton, Jeffrey S. Rush, Konstantin V. Korotkov, Beatrix Ueberheide, K. Heran Darwin Proc Natl Acad Sci U S A. 116(8): 3202–3210. Published online 2019 Feb 5. doi: 10.1073/pnas.1819468116 PMCID: PMC6386731

Movement dynamics of divisome proteins and PBP2x:FtsW in cells of Streptococcus pneumoniae Amilcar J. Perez, Yann Cesbron, Sidney L. Shaw, Jesus Bazan Villicana, Ho-Ching T. Tsui, Michael J. Boersma, Ziyun A. Ye, Yanina Tovpeko, Cees Dekker, Seamus Holden, Malcolm E. Winkler Proc Natl Acad Sci U S A. 116(8): 3211–3220. Published online 2019 Feb 4. doi: 10.1073/pnas.1816018116 PMCID: PMC6386697

Legionella pneumophila translocated translation inhibitors are required for bacterial-induced host cell cycle arrest Asaf Sol, Erion Lipo, Dennise A. de Jesús-Díaz, Connor Murphy, Mildred Devereux, Ralph R. Isberg Proc Natl Acad Sci U S A. 116(8): 3221–3228. Published online 2019 Feb 4. doi: 10.1073/pnas.1820093116 PMCID: PMC6386690

CD4 receptor diversity in chimpanzees protects against SIV infection Frederic Bibollet-Ruche, Ronnie M. Russell, Weimin Liu, Guillaume B. E. Stewart-Jones, Scott Sherrill-Mix, Yingying Li, Gerald H. Learn, Andrew G. Smith, Marcos V. P. Gondim, Lindsey J. Plenderleith, Julie M. Decker, Juliet L. Easlick, Katherine S. Wetzel, Ronald G. Collman, Shilei Ding, Andrés Finzi, Ahidjo Ayouba, Martine Peeters, Fabian H. Leendertz, Joost van Schijndel, Annemarie Goedmakers, Els Ton, Christophe Boesch, Hjalmar Kuehl, Mimi Arandjelovic, Paula Dieguez, Mizuki Murai, Christelle Colin, Kathelijne Koops, Sheri Speede, Mary K. Gonder, Martin N. Muller, Crickette M. Sanz, David B. Morgan, Rebecca Atencia, Debby Cox, Alex K. Piel, Fiona A. Stewart, Jean-Bosco N. Ndjango, Deus Mjungu, Elizabeth V. Lonsdorf, Anne E. Pusey, Peter D. Kwong, Paul M. Sharp, George M. Shaw, Beatrice H. Hahn Proc Natl Acad Sci U S A. 116(8): 3229–3238. Published online 2019 Feb 4. doi: 10.1073/pnas.1821197116 PMCID: PMC6386711

Neuroscience

Local homogeneity of tonotopic organization in the primary auditory cortex of marmosets Huan-huan Zeng, Jun-feng Huang, Ming Chen, Yun-qing Wen, Zhi-ming Shen, Mu-ming Poo Proc Natl Acad Sci U S A. 116(8): 3239–3244. Published online 2019 Feb 4. doi: 10.1073/pnas.1816653116 PMCID: PMC6386663

Genetically eliminating Purkinje neuron GABAergic neurotransmission increases their response gain to vestibular motion Trace L. Stay, Jean Laurens, Roy V. Sillitoe, Dora E. Angelaki Proc Natl Acad Sci U S A. 116(8): 3245–3250. Published online 2019 Feb 5. doi: 10.1073/pnas.1818819116 PMCID: PMC6386715

Persistent metabolic youth in the aging female brain Manu S. Goyal, Tyler M. Blazey, Yi Su, Lars E. Couture, Tony J. Durbin, Randall J. Bateman, Tammie L.-S. Benzinger, John C. Morris, Marcus E. Raichle, Andrei G. Vlassenko Proc Natl Acad Sci U S A. 116(8): 3251–3255. Published online 2019 Feb 4. doi: 10.1073/pnas.1815917116 PMCID: PMC6386682

TrkB-expressing neurons in the dorsomedial hypothalamus are necessary and sufficient to suppress homeostatic feeding Guey-Ying Liao, Clint E. Kinney, Juan Ji An, Baoji Xu Proc Natl Acad Sci U S A. 116(8): 3256–3261. Published online 2019 Feb 4. doi: 10.1073/pnas.1815744116 PMCID: PMC6386673

Presynaptic SNAP-25 regulates retinal waves and retinogeniculate projection via phosphorylation Yu-Tien Hsiao, Wen-Chi Shu, Pin-Chun Chen, Hui-Ju Yang, Hsin-Yo Chen, Sheng-Ping Hsu, Yi-Ting Huang, Cheng-Chang Yang, Yen-Ju Chen, Ni-Yen Yu, Shih-Yuan Liou, Ning Chiang, Chien-Ting Huang, Tzu-Lin Cheng, Lam-Yan Cheung, Yu-Chun Lin, Juu-Chin Lu, Chih-Tien Wang Proc Natl Acad Sci U S A. 116(8): 3262–3267. Published online 2019 Feb 6. doi: 10.1073/pnas.1812169116 PMCID: PMC6386712

High-dimensional representation of texture in somatosensory cortex of primates Justin D. Lieber, Sliman J. Bensmaia Proc Natl Acad Sci U S A. 116(8): 3268–3277. Published online 2019 Feb 4. doi: 10.1073/pnas.1818501116 PMCID: PMC6386651

Inositol hexakisphosphate kinase 3 promotes focal adhesion turnover via interactions with dynein intermediate chain 2 Tomas Rojas, Weiwei Cheng, Zhe Gao, Xiaoqi Liu, Yakun Wang, Adarsha P. Malla, Alfred C. Chin, Lewis H. Romer, Solomon H. Snyder, Chenglai Fu Proc Natl Acad Sci U S A. 116(8): 3278–3287. Published online 2019 Feb 4. doi: 10.1073/pnas.1817001116 PMCID: PMC6386689

Pharmacology

Diverse GPCRs exhibit conserved water networks for stabilization and activation A. J. Venkatakrishnan, Anthony K. Ma, Rasmus Fonseca, Naomi R. Latorraca, Brendan Kelly, Robin M. Betz, Chaitanya Asawa, Brian K. Kobilka, Ron O. Dror Proc Natl Acad Sci U S A. 116(8): 3288–3293. Published online 2019 Feb 6. doi: 10.1073/pnas.1809251116 PMCID: PMC6386714

Ca2+ allostery in PTH-receptor signaling Alex D. White, Fei Fang, Frédéric G. Jean-Alphonse, Lisa J. Clark, Hyun-Jung An, Hongda Liu, Yang Zhao, Shelley L. Reynolds, Sihoon Lee, Kunhong Xiao, Ieva Sutkeviciute, Jean-Pierre Vilardaga Proc Natl Acad Sci U S A. 116(8): 3294–3299. Published online 2019 Feb 4. doi: 10.1073/pnas.1814670116 PMCID: PMC6386702

Physiology

Design–functionality relationships for adhesion/growth-regulatory galectins Anna-Kristin Ludwig, Malwina Michalak, Qi Xiao, Ulrich Gilles, Francisco J. Medrano, Hanyue Ma, Forrest G. FitzGerald, William D. Hasley, Adriel Melendez-Davila, Matthew Liu, Khosrow Rahimi, Nina Yu Kostina, Cesar Rodriguez-Emmenegger, Martin Möller, Ingo Lindner, Herbert Kaltner, Mare Cudic, Dietmar Reusch, Jürgen Kopitz, Antonio Romero, Stefan Oscarson, Michael L. Klein, Hans-Joachim Gabius, Virgil Percec Proc Natl Acad Sci U S A. 116(8): 2837–2842. Published online 2019 Feb 4. doi: 10.1073/pnas.1813515116 PMCID: PMC6386680

Metabolic preference of nitrate over oxygen as an electron acceptor in foraminifera from the Peruvian oxygen minimum zone Nicolaas Glock, Alexandra-Sophie Roy, Dennis Romero, Tanita Wein, Julia Weissenbach, Niels Peter Revsbech, Signe Høgslund, David Clemens, Stefan Sommer, Tal Dagan Proc Natl Acad Sci U S A. 116(8): 2860–2865. Published online 2019 Feb 6. doi: 10.1073/pnas.1813887116 PMCID: PMC6386669

Plant Biology

Regulatory cascade involving transcriptional and N-end rule pathways in rice under submergence Chih-Cheng Lin, Ya-Ting Chao, Wan-Chieh Chen, Hsiu-Yin Ho, Mei-Yi Chou, Ya-Ru Li, Yu-Lin Wu, Hung-An Yang, Hsiang Hsieh, Choun-Sea Lin, Fu-Hui Wu, Shu-Jen Chou, Hao-Chung Jen, Yung-Hsiang Huang, Deli Irene, Wen-Jin Wu, Jian-Li Wu, Daniel J. Gibbs, Meng-Chiao Ho, Ming-Che Shih Proc Natl Acad Sci U S A. 116(8): 3300–3309. Published online 2019 Feb 5. doi: 10.1073/pnas.1818507116 PMCID: PMC6386710

Psychological and Cognitive Sciences

Frequency tagging cannot measure neural tracking of beat or meter Vani G. Rajendran, Jan W. H. Schnupp Proc Natl Acad Sci U S A. 116(8): 2779–2780. Published online 2019 Jan 29. doi: 10.1073/pnas.1820020116 PMCID: PMC6386709

Reply to Rajendran and Schnupp: Frequency tagging is sensitive to the temporal structure of signals Tomas Lenc, Peter E. Keller, Manuel Varlet, Sylvie Nozaradan Proc Natl Acad Sci U S A. 116(8): 2781–2782. Published online 2019 Jan 29. doi: 10.1073/pnas.1820941116 PMCID: PMC6386670

Music training, music aptitude, and speech perception E. Glenn Schellenberg Proc Natl Acad Sci U S A. 116(8): 2783–2784. Published online 2019 Jan 29. doi: 10.1073/pnas.1821109116 PMCID: PMC6386686

Reply to Schellenberg: Is there more to auditory plasticity than meets the ear? Gavin M. Bidelman, Kelsey Mankel Proc Natl Acad Sci U S A. 116(8): 2785–2786. Published online 2019 Jan 29. doi: 10.1073/pnas.1900068116 PMCID: PMC6386652

Musical reward prediction errors engage the nucleus accumbens and motivate learning Benjamin P. Gold, Ernest Mas-Herrero, Yashar Zeighami, Mitchel Benovoy, Alain Dagher, Robert J. Zatorre Proc Natl Acad Sci U S A. 116(8): 3310–3315. Published online 2019 Feb 6. doi: 10.1073/pnas.1809855116 PMCID: PMC6386687

Hippocampal atrophy and intrinsic brain network dysfunction relate to alterations in mind wandering in neurodegeneration Claire O’Callaghan, James M. Shine, John R. Hodges, Jessica R. Andrews-Hanna, Muireann Irish Proc Natl Acad Sci U S A. 116(8): 3316–3321. Published online 2019 Feb 4. doi: 10.1073/pnas.1818523116 PMCID: PMC6386688

Sustainability Science

Impacts of the Northwest Forest Plan on forest composition and bird populations Benjamin T. Phalan, Joseph M. Northrup, Zhiqiang Yang, Robert L. Deal, Josée S. Rousseau, Thomas A. Spies, Matthew G. Betts Proc Natl Acad Sci U S A. 116(8): 3322–3327. Published online 2019 Feb 4. doi: 10.1073/pnas.1813072116 PMCID: PMC6386667

Systems Biology

Consecutive feedback-driven constitutional dynamic networks Liang Yue, Shan Wang, Verena Wulf, Sivan Lilienthal, Françoise Remacle, R. D. Levine, Itamar Willner Proc Natl Acad Sci U S A. 116(8): 2843–2848. Published online 2019 Feb 6. doi: 10.1073/pnas.1816670116 PMCID: PMC6386722

Genome-wide colocalization of RNA–DNA interactions and fusion RNA pairs Zhangming Yan, Norman Huang, Weixin Wu, Weizhong Chen, Yiqun Jiang, Jingyao Chen, Xuerui Huang, Xingzhao Wen, Jie Xu, Qiushi Jin, Kang Zhang, Zhen Chen, Shu Chien, Sheng Zhong Proc Natl Acad Sci U S A. 116(8): 3328–3337. Published online 2019 Feb 4. doi: 10.1073/pnas.1819788116 PMCID: PMC6386723

Corrections