Police said Friday they have arrested four people after seizing a kilogram of cocaine, and about 36 kilograms of marijuana in two separate seizures on the same day at a St. John's business.

The Combined Forces Special Enforcement unit said a 19-year-old man from St. John's was arrested at 11 p.m. Thursday, after a two-month investigation.

Police found the cocaine, 18 kilograms of marijuana, $10,000 in cash, two handguns and a bullet proof vest.

The man is charged with trafficking, possession for the purpose of trafficking, and several weapons related offences.

Three others were picked up in a separate arrest at the same business earlier on Thursday.

Police said two men, 23 and 24, were arrested along with a 22-year-old woman. They were arrested around 4 p.m. and charged with trafficking and possession.

That bust netted 18 kilograms of marijuana.

Supt. Marlene Jesso of the Combined Forces Special Enforcement Unit said all four people were arrested at the same business, at different times of the day. (CBC)

In both cases, police said the drugs were in suitcases, and is worth a combined total of $290,000 on the street.

The guns were a 38 mm special, which police said was stolen, and 9 mm.

"We still have a lot of work to do. Possibly it could lead to other arrests," said Supt. Marlene Jesso, an investigator with the joint RCMP/RNC unit.

Jesso said police are not connecting the two seizures, although one investigation led to the other.

She would not name the business where the drugs were discovered.